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Product details

Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-20] - BSA and Azide free (Capture)

Catalog number HA721232

Price for HA721232

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Size / count 100 µL

About this product

Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Plays an important role in connecting T cell-mediated adaptive immunity and acute inflammatory response to destroy extracellular bacteria and fungi. As a signature effector cytokine of T-helper 17 cells (Th17), primarily induces neutrophil activation and recruitment at infection and inflammatory sites. In airway epithelium, mediates neutrophil chemotaxis via induction of CXCL1 and CXCL5 chemokines. In secondary lymphoid organs, contributes to germinal center formation by regulating the chemotactic response of B cells to CXCL12 and CXCL13, enhancing retention of B cells within the germinal centers, B cell somatic hypermutation rate and selection toward plasma cells. Effector cytokine of a subset of gamma-delta T cells that functions as part of an inflammatory circuit downstream IL1B, TLR2 and IL23A-IL12B to promote neutrophil recruitment for efficient bacterial clearance. Effector cytokine of innate immune cells including invariant natural killer cell (iNKT) and group 3 innate lymphoid cells that mediate initial neutrophilic inflammation. Involved in the maintenance of the integrity of epithelial barriers during homeostasis and pathogen infection.

Specifications

Catalog number
HA721232
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CTLA 8 antibody CTLA-8 antibody CTLA8 antibody cytotoxic T lymphocyte associated antigen 8 antibody Cytotoxic T lymphocyte associated protein 8 antibody Cytotoxic T lymphocyte associated serine esterase 8 antibody Cytotoxic T-lymphocyte-associated antigen 8 antibody IL 17 antibody IL 17A antibody IL-17 antibody IL-17A antibody IL17 antibody IL17_HUMAN antibody Il17a antibody Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody interleukin 17A antibody Interleukin-17A antibody interleukin17 antibody Interleukin17A antibody OTTHUMP00000016597 antibody OTTMUSP00000046003 antibody
Abbreviation
Interleukin-17A IL17 IL-17 IL17A IL-17A Cytotoxic T-lymphocyte-associated antigen 8 (CTLA-8) CTLA8
Swiss Prot
Q16552 Human
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant full length protein.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
ELISA (Cap)
Positive Control
Recombinant IL-17A protein.
Concentration
1 mg/mL
Dilution
ELISA (Cap): Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4).
Molecular Weight
Predicted band size: 17.5 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-20] - BSA and Azide free (Capture)?

The catalog number for Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-20] - BSA and Azide free (Capture) is HA721232.

What sizes are available for Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-20] - BSA and Azide free (Capture)?

Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-20] - BSA and Azide free (Capture) is available in the following size(s): 100 µL.

Is Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-20] - BSA and Azide free (Capture) in stock?

Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-20] - BSA and Azide free (Capture) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-20] - BSA and Azide free (Capture) used for?

Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Plays an important role in connecting T cell-mediated adaptive immunity and acute inflammatory response to destroy extracellular bacteria and fungi. As a signature effec

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

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