Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-24] - BSA and Azide free (Detector)

Catalog number HA721233

Price for HA721233

Size / count 100 µL

About this product

Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Plays an important role in connecting T cell-mediated adaptive immunity and acute inflammatory response to destroy extracellular bacteria and fungi. As a signature effector cytokine of T-helper 17 cells (Th17), primarily induces neutrophil activation and recruitment at infection and inflammatory sites. In airway epithelium, mediates neutrophil chemotaxis via induction of CXCL1 and CXCL5 chemokines. In secondary lymphoid organs, contributes to germinal center formation by regulating the chemotactic response of B cells to CXCL12 and CXCL13, enhancing retention of B cells within the germinal centers, B cell somatic hypermutation rate and selection toward plasma cells. Effector cytokine of a subset of gamma-delta T cells that functions as part of an inflammatory circuit downstream IL1B, TLR2 and IL23A-IL12B to promote neutrophil recruitment for efficient bacterial clearance. Effector cytokine of innate immune cells including invariant natural killer cell (iNKT) and group 3 innate lymphoid cells that mediate initial neutrophilic inflammation. Involved in the maintenance of the integrity of epithelial barriers during homeostasis and pathogen infection.

Specifications

Catalog number: HA721233
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CTLA 8 antibody CTLA-8 antibody CTLA8 antibody cytotoxic T lymphocyte associated antigen 8 antibody Cytotoxic T lymphocyte associated protein 8 antibody Cytotoxic T lymphocyte associated serine esterase 8 antibody Cytotoxic T-lymphocyte-associated antigen 8 antibody IL 17 antibody IL 17A antibody IL-17 antibody IL-17A antibody IL17 antibody IL17_HUMAN antibody Il17a antibody Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody interleukin 17A antibody Interleukin-17A antibody interleukin17 antibody Interleukin17A antibody OTTHUMP00000016597 antibody OTTMUSP00000046003 antibody
Abbreviation: Interleukin-17A IL17 IL-17 IL17A IL-17A Cytotoxic T-lymphocyte-associated antigen 8 (CTLA-8) CTLA8
Swiss Prot: Q16552 Human
Cellular Locus: Secreted.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant full length protein.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: ELISA (Det)
Positive Control: Recombinant IL-17A protein.
Concentration: 1 mg/mL
Dilution: ELISA (Det): Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4).
Molecular Weight: Predicted band size: 17.5 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-24] - BSA and Azide free (Detector)?

The catalog number for Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-24] - BSA and Azide free (Detector) is HA721233.

What sizes are available for Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-24] - BSA and Azide free (Detector)?

Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-24] - BSA and Azide free (Detector) is available in the following size(s): 100 µL.

Is Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-24] - BSA and Azide free (Detector) in stock?

Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-24] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Human IL-17A Recombinant Rabbit Monoclonal Antibody [PS01-24] - BSA and Azide free (Detector) used for?

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.