Claudin 1 Recombinant Rabbit Monoclonal Antibody [PS01-43]

Catalog number HA721248

Price for HA721248

Size / count 100 µL

About this product

Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions. Acts as a co-receptor for hepatitis C virus (HCV) in hepatocytes. Associates with CD81 and the CLDN1-CD81 receptor complex is essential for HCV entry into host cell.

Specifications

Catalog number: HA721248
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Claudin-1 antibody Claudin1 antibody CLD 1 antibody CLD1 antibody CLD1_HUMAN antibody CLDN 1 antibody Cldn1 antibody ILVASC antibody SEMP 1 antibody SEMP1 antibody Senescence associated epithelial membrane protein 1 antibody Senescence associated epithelial membrane protein antibody Senescence-associated epithelial membrane protein antibody
Abbreviation: Claudin-1 Senescence-associated epithelial membrane protein CLDN1 CLD1 SEMP1 UNQ481 PRO944
Swiss Prot: O95832 Human
Cellular Locus: Cell junction, Cell membrane, Membrane, Tight junction
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant full length protein within human Claudin 1.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IF-Tissue, IF-Cell
Positive Control: A431 cell lysate, HepG2 cell lysate, human tonsil tissue, human skin tissue, A431, HepG2.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:1,000 ;IF-Tissue: 1:200 ;IF-Cell: 1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 23 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Claudin 1 Recombinant Rabbit Monoclonal Antibody [PS01-43]?

The catalog number for Claudin 1 Recombinant Rabbit Monoclonal Antibody [PS01-43] is HA721248.

What sizes are available for Claudin 1 Recombinant Rabbit Monoclonal Antibody [PS01-43]?

Claudin 1 Recombinant Rabbit Monoclonal Antibody [PS01-43] is available in the following size(s): 100 µL.

Is Claudin 1 Recombinant Rabbit Monoclonal Antibody [PS01-43] in stock?

Claudin 1 Recombinant Rabbit Monoclonal Antibody [PS01-43] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Claudin 1 Recombinant Rabbit Monoclonal Antibody [PS01-43] used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.