Pyruvate Dehydrogenase E2 Recombinant Rabbit Monoclonal Antibody [JE34-38]

Catalog number HA721267

Price for HA721267

Size / count 100 µL

About this product

Dihydrolipoyl transacetylase (or dihydrolipoamide acetyltransferase) is an enzyme component of the multienzyme pyruvate dehydrogenase complex. The pyruvate dehydrogenase complex is responsible for the pyruvate decarboxylation step that links glycolysis to the citric acid cycle. This involves the transformation of pyruvate from glycolysis into acetyl-CoA which is then used in the citric acid cycle to carry out cellular respiration. There are three different enzyme components in the pyruvate dehydrogenase complex. Pyruvate dehydrogenase (EC 1.2.4.1) is responsible for the oxidation of pyruvate, dihydrolipoyl transacetylase (this enzyme; EC 2.3.1.12) transfers the acetyl group to coenzyme A (CoA), and dihydrolipoyl dehydrogenase (EC 1.8.1.4) regenerates the lipoamide. Because dihydrolipoyl transacetylase is the second of the three enzyme components participating in the reaction mechanism for conversion of pyruvate into acetyl CoA, it is sometimes referred to as E2. In humans, dihydrolipoyl transacetylase enzymatic activity resides in the pyruvate dehydrogenase complex component E2 (PDCE2) that is encoded by the DLAT (dihydrolipoamide S-acetyltransferase) gene.

Specifications

Catalog number: HA721267
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: 70 kDa mitochondrial autoantigen of primary biliary cirrhosis antibody Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex antibody Dihydrolipoamide S Acetyltransferase antibody Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex antibody dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial antibody DLAT antibody DLTA antibody E2 antibody E2 component of pyruvate dehydrogenase complex antibody M2 antigen complex 70 kDa subunit antibody mitochondrial antibody ODP2_HUMAN antibody PBC antibody PDC E2 antibody PDC-E2 antibody PDCE2 antibody Pyruvate dehydrogenase complex component E2 antibody Pyruvate dehydrogenase complex E2 subunit antibody
Abbreviation: DLAT, DLTA
Swiss Prot: P10515 Human, Q8BMF4 Mouse, P08461 Rat
Cellular Locus: Mitochondrion matrix.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human Pyruvate Dehydrogenase E2 aa 574-624/647.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: HL-60 cell lysate, Mouse heart tissue lysate, SK-Br-3 cell lysate, K562 cell lysate, Daudi cell lysate, human testis tissue, mouse cerebellum tissue, rat brain tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IHC-P: 1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 69 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Pyruvate Dehydrogenase E2 Recombinant Rabbit Monoclonal Antibody [JE34-38]?

The catalog number for Pyruvate Dehydrogenase E2 Recombinant Rabbit Monoclonal Antibody [JE34-38] is HA721267.

What sizes are available for Pyruvate Dehydrogenase E2 Recombinant Rabbit Monoclonal Antibody [JE34-38]?

Pyruvate Dehydrogenase E2 Recombinant Rabbit Monoclonal Antibody [JE34-38] is available in the following size(s): 100 µL.

Is Pyruvate Dehydrogenase E2 Recombinant Rabbit Monoclonal Antibody [JE34-38] in stock?

Pyruvate Dehydrogenase E2 Recombinant Rabbit Monoclonal Antibody [JE34-38] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Pyruvate Dehydrogenase E2 Recombinant Rabbit Monoclonal Antibody [JE34-38] used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.