TUBA3C Recombinant Rabbit Monoclonal Antibody [PSH0-14]

About this product

Tubulin alpha-3C/D chain is a protein that in humans is encoded by the TUBA3C gene. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. Alternative splicing has been observed for this gene and two variants have been identified.

Specifications

Catalog number

HA721272

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

TUBA3C TUBA2 Tubulin alpha-3C chain EC:3.6.5. Alpha-tubulin 2 Alpha-tubulin 3C Tubulin alpha-2 chain Detyrosinated tubulin alpha-3C chain

Abbreviation

TUBA3C, TUBA2

Swiss Prot

P0DPH7 Human

Cellular Locus

Cytoplasm, cytoskeleton.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within human TUBA3C aa 150-350 / 450.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

293T cell lysate, A431 cell lysate, HepG2 cell lysate, 293 cell lysate, Hela cell lysate, Jurkat cell lysate, SH-SY5Y cell lysate, human testis tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:2,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 50 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes