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![Phospho-eIF4G (S1108) Recombinant Rabbit Monoclonal Antibody [PS01-08] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8c061270361ea81ab0/imageurl/ha721276.webp)
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Product details
Catalog number HA721276
Price for HA721276
Size / count 100 µL
Eukaryotic translation initiation factor 4 G (eIF4G) is a protein involved in eukaryotic translation initiation and is a component of the eIF4F cap-binding complex. Orthologs of eIF4G have been studied in multiple species, including humans, yeast, and wheat. However, eIF4G is exclusively found in domain Eukarya, and not in domains Bacteria or Archaea, which do not have capped mRNA. As such, eIF4G structure and function may vary between species, although the human eIF4G 1 has been the focus of extensive studies. Across species, eIF4G strongly associates with eIF4E, the protein that directly binds the mRNA cap. Together with the RNA helicase protein eIF4A, these form the eIF4F complex. Within the cell eIF4G is found primarily in the cytoplasm, usually bound to eIF4E; however, it is also found in the nucleus, where its function is unknown. It may have a role in nonsense-mediated decay. eIF4G has been implicated in breast cancer. It appears in increased levels in certain types of breast cancer and increases production of mRNAs that contain IRESs; these mRNAs produce hypoxia- and stress-related proteins that encourage blood vessel invasion (which is important for tumorigenesis).
The catalog number for Phospho-eIF4G (S1108) Recombinant Rabbit Monoclonal Antibody [PS01-08] is HA721276.
Phospho-eIF4G (S1108) Recombinant Rabbit Monoclonal Antibody [PS01-08] is available in the following size(s): 100 µL.
Phospho-eIF4G (S1108) Recombinant Rabbit Monoclonal Antibody [PS01-08] is currently made to order / not held in immediate stock. Contact us for lead time.
Eukaryotic translation initiation factor 4 G (eIF4G) is a protein involved in eukaryotic translation initiation and is a component of the eIF4F cap-binding complex. Orthologs of eIF4G have been studied in multiple species, including humans, yeast, and wheat. However, eIF4G is exclusively found in do
Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.
Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.
Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.
