Aldehyde Oxidase Recombinant Rabbit Monoclonal Antibody [PSH0-17]

Catalog number HA721277

Price for HA721277

Size / count 100 µL

About this product

Aldehyde oxidase 1 is an enzyme that in humans is encoded by the AOX1 gene. Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis.

Specifications

Catalog number: HA721277
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Aldehyde oxidase 1 antibody AO antibody AOH1 antibody AOX 1 antibody azaheterocycle hydroxylase antibody EC 1.2.3.1 antibody
Abbreviation: AOX1, AO
Swiss Prot: Q06278 Human, O54754 Mouse, Q9Z0U5 Rat
Cellular Locus: Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human AOX1 aa 1,301-1,338 / 1,338.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: Rat liver tissue lysates, rat liver tissue, rat adrenal gland tissue, human kidney tissue, mouse testis tissue, Hela.
Concentration: 1 mg/mL
Dilution: WB: 1:500 ;IHC-P: 1:200-1:1,000 ;FC: 1:500-1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 148 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Aldehyde Oxidase Recombinant Rabbit Monoclonal Antibody [PSH0-17]?

The catalog number for Aldehyde Oxidase Recombinant Rabbit Monoclonal Antibody [PSH0-17] is HA721277.

What sizes are available for Aldehyde Oxidase Recombinant Rabbit Monoclonal Antibody [PSH0-17]?

Aldehyde Oxidase Recombinant Rabbit Monoclonal Antibody [PSH0-17] is available in the following size(s): 100 µL.

Is Aldehyde Oxidase Recombinant Rabbit Monoclonal Antibody [PSH0-17] in stock?

Aldehyde Oxidase Recombinant Rabbit Monoclonal Antibody [PSH0-17] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Aldehyde Oxidase Recombinant Rabbit Monoclonal Antibody [PSH0-17] used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.