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![Human IL-1 beta Recombinant Rabbit Monoclonal Antibody [PS01-39] - BSA and Azide free (Capture) — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea81838/imageurl/ha721278.webp)
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Product details
Catalog number HA721278
Price for HA721278
Size / count 100 µL
Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a cytokine protein that in humans is encoded by the IL1B gene. There are two genes for interleukin-1 (IL-1): IL-1 alpha and IL-1 beta (this gene). IL-1β precursor is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase) to form mature IL-1β. Increased production of IL-1β causes a number of different autoinflammatory syndromes, most notably the monogenic conditions referred to as Cryopyrin-Associated Periodic Syndromes (CAPS), due to mutations in the inflammasome receptor NLRP3 which triggers processing of IL-1B. Intestinal dysbiosis has been observed to induce osteomyelitis through a IL-1β dependent manner. The presence of IL-1β has been also found in patients with multiple sclerosis (a chronic autoimmune disease of the central nervous system). However, it is not known exactly which cells produce IL-1β. Treatment of multiple sclerosis with glatiramer acetate or natalizumab has also been shown to reduce the presence of IL-1β or its receptor.[18]
The catalog number for Human IL-1 beta Recombinant Rabbit Monoclonal Antibody [PS01-39] - BSA and Azide free (Capture) is HA721278.
Human IL-1 beta Recombinant Rabbit Monoclonal Antibody [PS01-39] - BSA and Azide free (Capture) is available in the following size(s): 100 µL.
Human IL-1 beta Recombinant Rabbit Monoclonal Antibody [PS01-39] - BSA and Azide free (Capture) is currently made to order / not held in immediate stock. Contact us for lead time.
Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a cytokine protein that in humans is encoded by the IL1B gene. There are two genes for interleukin-1 (IL-1): IL-1 alpha and IL-1 beta
Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.
Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.
Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.
