- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
![Human IL-1 beta Recombinant Rabbit Monoclonal Antibody [PS00-82] - BSA and Azide free (Detector) — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea81772/imageurl/ha721279.webp)
Select the image to view it full size.
Product details
Catalog number HA721279
Price for HA721279
Size / count 100 µL
Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a cytokine protein that in humans is encoded by the IL1B gene. There are two genes for interleukin-1 (IL-1): IL-1 alpha and IL-1 beta (this gene). IL-1β precursor is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase) to form mature IL-1β. Increased production of IL-1β causes a number of different autoinflammatory syndromes, most notably the monogenic conditions referred to as Cryopyrin-Associated Periodic Syndromes (CAPS), due to mutations in the inflammasome receptor NLRP3 which triggers processing of IL-1B. Intestinal dysbiosis has been observed to induce osteomyelitis through a IL-1β dependent manner. The presence of IL-1β has been also found in patients with multiple sclerosis (a chronic autoimmune disease of the central nervous system). However, it is not known exactly which cells produce IL-1β. Treatment of multiple sclerosis with glatiramer acetate or natalizumab has also been shown to reduce the presence of IL-1β or its receptor.[18]
The catalog number for Human IL-1 beta Recombinant Rabbit Monoclonal Antibody [PS00-82] - BSA and Azide free (Detector) is HA721279.
Human IL-1 beta Recombinant Rabbit Monoclonal Antibody [PS00-82] - BSA and Azide free (Detector) is available in the following size(s): 100 µL.
Human IL-1 beta Recombinant Rabbit Monoclonal Antibody [PS00-82] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.
Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a cytokine protein that in humans is encoded by the IL1B gene. There are two genes for interleukin-1 (IL-1): IL-1 alpha and IL-1 beta
Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.
Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.
Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.
