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![Human IL-2 Receptor alpha Recombinant Rabbit Monoclonal Antibody [PS00-52] - BSA and Azide free (Capture) — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea80e1c/imageurl/ha721280.webp)
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Product details
Catalog number HA721280
Price for HA721280
Size / count 100 µL
Interleukin-2 receptor alpha chain (also called CD25) is the human protein encoded by the IL2RA gene. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolysis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is currently unknown. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. IL2RA is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, mastocytosis and tumor infiltrating lymphocytes. It functions as the receptor for HTLV-1 and is consequently expressed on neoplastic cells in adult T cell lymphoma/leukemia. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression. Infection by the protozoan Trypanosoma cruzi causes Chagas disease, characterized by a reduction in the amount of IL2RA expressed on the surface of immune cells. This leads to chronic immune suppression, becoming increasingly severe over the course of many years and ultimately resulting in death if left untreated.
The catalog number for Human IL-2 Receptor alpha Recombinant Rabbit Monoclonal Antibody [PS00-52] - BSA and Azide free (Capture) is HA721280.
Human IL-2 Receptor alpha Recombinant Rabbit Monoclonal Antibody [PS00-52] - BSA and Azide free (Capture) is available in the following size(s): 100 µL.
Human IL-2 Receptor alpha Recombinant Rabbit Monoclonal Antibody [PS00-52] - BSA and Azide free (Capture) is currently made to order / not held in immediate stock. Contact us for lead time.
Interleukin-2 receptor alpha chain (also called CD25) is the human protein encoded by the IL2RA gene. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) resu
A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.
Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.
