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Product details

GM130 Recombinant Rabbit Monoclonal Antibody [JE42-53]

Catalog number HA721282

Price for HA721282

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Size / count 100 µL

About this product

Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus, and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane. Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Golgi disassembly. Also plays a key role in spindle pole assembly and centrosome organization. Promotes the mitotic spindle pole assembly by activating the spindle assembly factor TPX2 to nucleate microtubules around the Golgi and capture them to couple mitotic membranes to the spindle. TPX2 then activates AURKA kinase and stimulates local microtubule nucleation. Upon filament assembly, nascent microtubules are further captured by GOLGA2, thus linking Golgi membranes to the spindle. Regulates the meiotic spindle pole assembly, probably via the same mechanism. Also regulates the centrosome organization. Also required for the Golgi ribbon formation and glycosylation of membrane and secretory proteins.

Specifications

Catalog number
HA721282
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
30 kDa cis Golgi matrix protein antibody 130 kDa cis-Golgi matrix protein antibody Cis golgi matrix protein GM130 antibody GM130 antibody Gm130 autoantigen antibody GOGA2_HUMAN antibody GOLGA 2 antibody Golga2 antibody Golgi autoantigen antibody Golgi autoantigen golgin subfamily a 2 antibody Golgi matrix protein GM130 antibody Golgin 95 antibody golgin A2 antibody Golgin subfamily a 2 antibody Golgin subfamily A member 2 antibody Golgin-95 antibody MGC20672 antibody SY11 protein antibody
Abbreviation
GM130, GOLGA2
Swiss Prot
Q08379 Human, Q921M4 Mouse, Q62839 Rat
Cellular Locus
Cytoplasm, Cytoskeleton, Membrane, Microtubule.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human GM130 aa 1-100 (N terminal).
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
MCF-7 cell lysates, mouse kidney tissue, rat kidney tissue, MCF7.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:1,000 ;IF-Cell: 1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 113 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for GM130 Recombinant Rabbit Monoclonal Antibody [JE42-53]?

The catalog number for GM130 Recombinant Rabbit Monoclonal Antibody [JE42-53] is HA721282.

What sizes are available for GM130 Recombinant Rabbit Monoclonal Antibody [JE42-53]?

GM130 Recombinant Rabbit Monoclonal Antibody [JE42-53] is available in the following size(s): 100 µL.

Is GM130 Recombinant Rabbit Monoclonal Antibody [JE42-53] in stock?

GM130 Recombinant Rabbit Monoclonal Antibody [JE42-53] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GM130 Recombinant Rabbit Monoclonal Antibody [JE42-53] used for?

Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus, and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane. Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at the

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

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