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Product details

14-3-3 alpha+beta Mouse Monoclonal Antibody [9-26]

Catalog number M0407-14

Price for M0407-14

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Size / count 100 µL

About this product

The 14-3-3 proteins are a family of proteins involved in the regulation of apoptosis, mitogenic signaling and cell-cycle checkpoints. The 14-3-3 proteins are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins. Through binding Bad, 14-3-3 prevents apoptosis by sequestering Bad to the cytosol. The 14-3-3 proteins are also Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. They bind to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

Specifications

Catalog number
M0407-14
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
14 3 3 alpha antibody 14 3 3 protein beta/alpha antibody 14-3-3 protein beta/alpha antibody 1433B_HUMAN antibody Brain protein 14 3 3 beta isoform antibody GW128 antibody HS 1 antibody KCIP-1 antibody KCIP1 antibody N-terminally processed antibody Protein 1054 antibody Protein kinase C inhibitor protein 1 antibody YWHAA antibody YWHAB antibody
Swiss Prot
P31946 Human
Cellular Locus
Cytoplasm, Membrane, Vacuole.
Host
Mouse
Species Reactivity
Human, Mouse, Zebrafish, Rat
Immunogen
Recombinant protein within Human 14-3-3 b / a aa 1-246 / 246.
Isotype
IgG2a
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
A549 cell lysates, mouse liver tissue lysates, hybrid fish (crucian-carp) brain tissue lysates, 293T, human breast carcinoma tissue, Zebrafish tissue.
Concentration
2 mg/mL
Dilution
WB: 1:1,000-1:5,000 ;IF-Cell: 1:50-1:100 ;IHC-P: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 28 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for 14-3-3 alpha+beta Mouse Monoclonal Antibody [9-26]?

The catalog number for 14-3-3 alpha+beta Mouse Monoclonal Antibody [9-26] is M0407-14.

What sizes are available for 14-3-3 alpha+beta Mouse Monoclonal Antibody [9-26]?

14-3-3 alpha+beta Mouse Monoclonal Antibody [9-26] is available in the following size(s): 100 µL.

Is 14-3-3 alpha+beta Mouse Monoclonal Antibody [9-26] in stock?

14-3-3 alpha+beta Mouse Monoclonal Antibody [9-26] is currently made to order / not held in immediate stock. Contact us for lead time.

What is 14-3-3 alpha+beta Mouse Monoclonal Antibody [9-26] used for?

The 14-3-3 proteins are a family of proteins involved in the regulation of apoptosis, mitogenic signaling and cell-cycle checkpoints. The 14-3-3 proteins are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins. Through binding B

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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