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Product details

FAM38A/PIEZO1 Mouse Monoclonal Antibody [2-10]

Catalog number M1005-2

Price for M1005-2

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Size / count 100 µL

About this product

Pore-forming subunit of a mechanosensitive non-specific cation channel. Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling. In the kidney, may contribute to the detection of intraluminal pressure changes and to urine flow sensing. Acts as shear-stress sensor that promotes endothelial cell organization and alignment in the direction of blood flow through calpain activation. Plays a key role in blood vessel formation and vascular structure in both development and adult physiology.

Specifications

Catalog number
M1005-2
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
DHS Fam38a Family with sequence similarity 38 member A KIAA0233 Membrane protein induced by beta-amyloid treatment Mib PIEZ1_HUMAN Piezo-type mechanosensitive ion channel component 1 PIEZO1 Protein FAM38A Protein FAM38B Protein PIEZO1
Abbreviation
Mib, PIEZO1, FAM38A, KIAA0233
Swiss Prot
Q92508 Human, E2JF22 Mouse, Q0KL00 Rat
Cellular Locus
Endoplasmic reticulum membrane. Cell membrane.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Protein FAM38A aa 1275-1540 / 2521.
Isotype
IgG2a
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
MCF-7, Hela, Siha, A431, mouse brain tissue, rat brain tissue, rat hippocampus tissue.
Concentration
2 mg/mL
Dilution
WB: 1:500-1:2,000 ;IF-Cell: 1:100 ;IHC-P: 1:200-1:600
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 287 kD
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for FAM38A/PIEZO1 Mouse Monoclonal Antibody [2-10]?

The catalog number for FAM38A/PIEZO1 Mouse Monoclonal Antibody [2-10] is M1005-2.

What sizes are available for FAM38A/PIEZO1 Mouse Monoclonal Antibody [2-10]?

FAM38A/PIEZO1 Mouse Monoclonal Antibody [2-10] is available in the following size(s): 100 µL.

Is FAM38A/PIEZO1 Mouse Monoclonal Antibody [2-10] in stock?

FAM38A/PIEZO1 Mouse Monoclonal Antibody [2-10] is currently made to order / not held in immediate stock. Contact us for lead time.

What is FAM38A/PIEZO1 Mouse Monoclonal Antibody [2-10] used for?

Pore-forming subunit of a mechanosensitive non-specific cation channel. Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitm

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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