CD80/B7-1 Mouse Monoclonal Antibody [8-E5] — image 1 of 3

Product details

CD80/B7-1 Mouse Monoclonal Antibody [8-E5]

Catalog number M1007-10

Price for M1007-10

Size / count 100 µL

About this product

CD80/B7-1 is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. After engagement of T-cell receptor with antigen in association with major histocompatibility complex class II, a second signal mediated through the binding of B7 to CD28 greatly upregulates the production of multiple lymphokines. B7-1 is a costimulatory molecule for the activation of both CD4+ and CD8+ T lymphocytes that prevents the induction of clonal anergy. Thus, the transfer of B7-1 genes into tumor cells can induce protective immunity and lead to tumor rejection of some tumors in model systems of in vivo tumor growth.

Specifications

Catalog number: M1007-10
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Activation B7-1 antigen antibody B lymphocyte activation antigen B7 antibody B7 antibody B7-1 antibody B7-1 antigen antibody B7.1 antibody BB1 antibody CD28 antigen ligand 1 antibody CD28LG antibody CD28LG1 antibody CD80 antibody CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) antibody CD80 antigen antibody CD80 molecule antibody CD80_HUMAN antibody Costimulatory factor CD80 antibody costimulatory molecule variant IgV-CD80 antibody CTLA-4 counter-receptor B7.1 antibody LAB7 antibody T-lymphocyte activation antigen CD80 antibody
Abbreviation: CD80, CD28LG, CD28LG1, LAB7
Swiss Prot: P33681 Human, Q00609 Mouse
Cellular Locus: Membrane.
Host: Mouse
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within human CD80 aa 74-118 / 288.
Isotype: IgG2b
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: Human brain tissue lysates, human brain tissue, SH-SY5Y, Hela.
Concentration: 2 mg/mL
Dilution: WB: 1:1,000 ;IF-Cell: 1:100-1:200 ;IHC-P: 1:50
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 33 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for CD80/B7-1 Mouse Monoclonal Antibody [8-E5]?

The catalog number for CD80/B7-1 Mouse Monoclonal Antibody [8-E5] is M1007-10.

What sizes are available for CD80/B7-1 Mouse Monoclonal Antibody [8-E5]?

CD80/B7-1 Mouse Monoclonal Antibody [8-E5] is available in the following size(s): 100 µL.

Is CD80/B7-1 Mouse Monoclonal Antibody [8-E5] in stock?

CD80/B7-1 Mouse Monoclonal Antibody [8-E5] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD80/B7-1 Mouse Monoclonal Antibody [8-E5] used for?

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.