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Product details

ATRX Mouse Monoclonal Antibody [2-E7]

Catalog number M1311-2

Price for M1311-2

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Size / count 100 µL

About this product

Transcriptional regulator ATRX contains an ATPase / helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations of the ATRX gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes.

Specifications

Catalog number
M1311-2
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Alpha thalassemia/mental retardation syndrome X linked homolog antibody ATP dependent helicase ATRX antibody ATP-dependent helicase ATRX antibody ATR2 antibody Atrx antibody ATRX_HUMAN antibody DNA dependent ATPase and helicase antibody Helicase 2, X linked antibody MGC2094 antibody MRXHF1 antibody RAD54 antibody RAD54L antibody SFM1 antibody SHS antibody Transcriptional regulator ATRX antibody X linked helicase II antibody X linked nuclear protein antibody X-linked helicase II antibody X-linked nuclear protein antibody XH2 antibody XNP antibody Znf HX antibody Znf-HX antibody
Abbreviation
Atrx
Swiss Prot
Q61687 Mouse
Cellular Locus
Nucleus
Host
Mouse
Species Reactivity
Mouse
Immunogen
Recombinant protein within mouse ATRX aa 2,236-2,416 / 2,476.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
IF-Cell, IHC-P
Positive Control
NIH/3T3, mouse kidney tissue.
Concentration
2 mg/mL
Dilution
IF-Cell: 1:100 ;IHC-P: 1:200
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
280 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for ATRX Mouse Monoclonal Antibody [2-E7]?

The catalog number for ATRX Mouse Monoclonal Antibody [2-E7] is M1311-2.

What sizes are available for ATRX Mouse Monoclonal Antibody [2-E7]?

ATRX Mouse Monoclonal Antibody [2-E7] is available in the following size(s): 100 µL.

Is ATRX Mouse Monoclonal Antibody [2-E7] in stock?

ATRX Mouse Monoclonal Antibody [2-E7] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ATRX Mouse Monoclonal Antibody [2-E7] used for?

Transcriptional regulator ATRX contains an ATPase / helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its invol

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

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