Lin28B Mouse Monoclonal Antibody [A2-4-5] — image 1 of 2

Product details

Lin28B Mouse Monoclonal Antibody [A2-4-5]

Catalog number M1312-1

Price for M1312-1

Size / count 100 µL

About this product

LIN28 is thought to regulate the self-renewal of stem cells. In nematodes, the LIN28 homolog lin-28 is a heterochronic gene that determines the onset of early larval stages of developmental events in Caenorhabditis elegans, by regulating the self-renewal of nematode stem cells in the skin (called seam cells) and vulva (called VPCs) during development. In mice, LIN28 is highly expressed in mouse embryonic stem cells and during early embryogenesis.It acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Lin28B is high expression in testis, fetal liver, placenta and in hepatocellular carcinoma (HCC).

Specifications

Catalog number: M1312-1
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CSDD 2 antibody CSDD2 antibody FLJ16517 antibody Lin 28 homolog B (C. elegans) antibody Lin 28.2 antibody Lin-28B antibody LIN28B antibody LN28B_HUMAN antibody Protein lin-28 homolog B antibody
Abbreviation: Lin-28B
Swiss Prot: Q6ZN17 Human
Cellular Locus: Cytoplasm, nucleus
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant protein within Human Lin28B aa 73-250 / 250.
Isotype: IgG2a
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: JAR cell lysate, NCCIT, human placenta tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:1,000 ;IF-Cell: 1:100-1:200 ;IHC-P: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 27 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Lin28B Mouse Monoclonal Antibody [A2-4-5]?

The catalog number for Lin28B Mouse Monoclonal Antibody [A2-4-5] is M1312-1.

What sizes are available for Lin28B Mouse Monoclonal Antibody [A2-4-5]?

Lin28B Mouse Monoclonal Antibody [A2-4-5] is available in the following size(s): 100 µL.

Is Lin28B Mouse Monoclonal Antibody [A2-4-5] in stock?

Lin28B Mouse Monoclonal Antibody [A2-4-5] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Lin28B Mouse Monoclonal Antibody [A2-4-5] used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.