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![PODXL Mouse Monoclonal Antibody [D0-E8] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8d061270361ea821b7/imageurl/m1403-4.webp)
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Product details
Catalog number M1403-4
Price for M1403-4
Size / count 100 µL
Podocalyxin, a sialoglycoprotein, is thought to be the major constituent of the glycocalyx of podocytes. It is a member of the CD34 family of transmembrane sialomucins. It is involved in the regulation of both adhesion and cell morphology and cancer progression. It functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Podocalyxin acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Sialylated, O-glycosylated glycoforms of podocalyxin expressed by colon carcinoma cells possess L-selectin and E-selectin binding activity, and may be pivotal to the metastatic spread of colon carcinoma cells
The catalog number for PODXL Mouse Monoclonal Antibody [D0-E8] is M1403-4.
PODXL Mouse Monoclonal Antibody [D0-E8] is available in the following size(s): 100 µL.
PODXL Mouse Monoclonal Antibody [D0-E8] is currently made to order / not held in immediate stock. Contact us for lead time.
Podocalyxin, a sialoglycoprotein, is thought to be the major constituent of the glycocalyx of podocytes. It is a member of the CD34 family of transmembrane sialomucins. It is involved in the regulation of both adhesion and cell morphology and cancer progression. It functions as an anti-adhesive mole
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