PODXL Mouse Monoclonal Antibody [2-A4]

Catalog number M1403-5

Price for M1403-5

Size / count 100 µL

About this product

Podocalyxin, a sialoglycoprotein, is thought to be the major constituent of the glycocalyx of podocytes. It is a member of the CD34 family of transmembrane sialomucins. It is involved in the regulation of both adhesion and cell morphology and cancer progression. It functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Podocalyxin acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Sialylated, O-glycosylated glycoforms of podocalyxin expressed by colon carcinoma cells possess L-selectin and E-selectin binding activity, and may be pivotal to the metastatic spread of colon carcinoma cells.

Specifications

Catalog number: M1403-5
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: GCTM-2 antigen antibody Gp2 antibody Gp200 antibody MGC138240 antibody PC antibody PCLP antibody PCLP-1 antibody PCLP1 antibody Pcx antibody Podocalyxin antibody Podocalyxin like antibody Podocalyxin like protein antibody Podocalyxin-like protein 2 antibody Podxl antibody PODXL_HUMAN antibody
Abbreviation: PC,PCLP-1
Swiss Prot: O00592 Human
Cellular Locus: Apical cell membrane
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant protein within Human PODXL aa 1-500 / 558.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: IF-Cell, IHC-P
Positive Control: HCT116
Concentration: 2 mg/mL
Dilution: IF-Cell: 1:200-1:500
Purity: Protein G affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 58kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for PODXL Mouse Monoclonal Antibody [2-A4]?

The catalog number for PODXL Mouse Monoclonal Antibody [2-A4] is M1403-5.

What sizes are available for PODXL Mouse Monoclonal Antibody [2-A4]?

PODXL Mouse Monoclonal Antibody [2-A4] is available in the following size(s): 100 µL.

Is PODXL Mouse Monoclonal Antibody [2-A4] in stock?

PODXL Mouse Monoclonal Antibody [2-A4] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PODXL Mouse Monoclonal Antibody [2-A4] used for?

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.