E-cadherin Mouse Monoclonal Antibody [3-F9] — image 1 of 2

Product details

E-cadherin Mouse Monoclonal Antibody [3-F9]

Catalog number M1405-3

Price for M1405-3

Size / count 100 µL

About this product

E-cadherin (epithelial) is the most well-studied member of the cadherin family. It consists of 5 cadherin repeats (EC1 ~ EC5) in the extracellular domain, one transmembrane domain, and an intracellular domain that binds p120-catenin and beta-catenin. The intracellular domain contains a highly-phosphorylated region vital to beta-catenin binding and, therefore, to E-cadherin function. Loss of E-cadherin function or expression has been implicated in cancer progression and metastasis. E-cadherin downregulation decreases the strength of cellular adhesion within a tissue, resulting in an increase in cellular motility. This in turn may allow cancer cells to cross the basement membrane and invade surrounding tissues. E-cadherin is also used by pathologists to diagnose different kinds of breast cancer.

Specifications

Catalog number: M1405-3
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Arc 1 antibody CADH1_HUMAN antibody Cadherin 1 antibody cadherin 1 type 1 E-cadherin antibody Cadherin1 antibody CAM 120/80 antibody CD 324 antibody CD324 antibody CD324 antigen antibody cdh1 antibody CDHE antibody E-Cad/CTF3 antibody E-cadherin antibody ECAD antibody Epithelial cadherin antibody epithelial calcium dependant adhesion protein antibody LCAM antibody Liver cell adhesion molecule antibody UVO antibody Uvomorulin antibody
Abbreviation: E-cadherin
Swiss Prot: P12830 Human, P09803 Mouse
Cellular Locus: Cell membrane
Host: Mouse
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within mouse E-Cadherin aa 350-550.
Isotype: IgG2b
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: IHC-P
Positive Control: Human liver tissue, mouse liver tissue.
Concentration: 2 mg/mL
Dilution: IHC-P: 1:200
Purity: Protein G affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: ~130kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for E-cadherin Mouse Monoclonal Antibody [3-F9]?

The catalog number for E-cadherin Mouse Monoclonal Antibody [3-F9] is M1405-3.

What sizes are available for E-cadherin Mouse Monoclonal Antibody [3-F9]?

E-cadherin Mouse Monoclonal Antibody [3-F9] is available in the following size(s): 100 µL.

Is E-cadherin Mouse Monoclonal Antibody [3-F9] in stock?

E-cadherin Mouse Monoclonal Antibody [3-F9] is currently made to order / not held in immediate stock. Contact us for lead time.

What is E-cadherin Mouse Monoclonal Antibody [3-F9] used for?

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.