DNMT3L Mouse Monoclonal Antibody [B0-5] — image 1 of 3

Product details

DNMT3L Mouse Monoclonal Antibody [B0-5]

Catalog number M1405-4

Price for M1405-4

Size / count 100 µL

About this product

DNA (cytosine-5)-methyltransferase 3-like is an enzyme that in humans is encoded by the DNMT3L gene. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases. This protein is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, this protein does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and it is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1.

Specifications

Catalog number: M1405-4
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Cytosine 5 methyltransferase 3 like protein antibody DNA (cytosine 5 ) methyltransferase 3 like antibody DNA (cytosine-5)-methyltransferase 3-like antibody DNA cytosine 5 methyltransferase 3 like protein antibody DNA methyltransferase 3 like protein antibody DNM3L_HUMAN antibody Dnmt 3L antibody Dnmt3l antibody Human cytosine 5 methyltransferase 3 like protein antibody MGC1090 antibody
Abbreviation: DNMT3L
Swiss Prot: Q9UJW3 Human
Cellular Locus: Nucleus
Host: Mouse
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within human DNMT3L aa 1-250/386.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: IF-Cell, IHC-P
Positive Control: HepG2, NCCIT, mouse colon
Concentration: 2 mg/mL
Dilution: IF-Cell: 1:200-1:500;IHC-P: 1:200
Purity: Protein G affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 44kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for DNMT3L Mouse Monoclonal Antibody [B0-5]?

The catalog number for DNMT3L Mouse Monoclonal Antibody [B0-5] is M1405-4.

What sizes are available for DNMT3L Mouse Monoclonal Antibody [B0-5]?

DNMT3L Mouse Monoclonal Antibody [B0-5] is available in the following size(s): 100 µL.

Is DNMT3L Mouse Monoclonal Antibody [B0-5] in stock?

DNMT3L Mouse Monoclonal Antibody [B0-5] is currently made to order / not held in immediate stock. Contact us for lead time.

What is DNMT3L Mouse Monoclonal Antibody [B0-5] used for?

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.