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Product details

Claudin 7 Mouse Monoclonal Antibody [6-G3]

Catalog number M1412-2

Price for M1412-2

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Size / count 100 µL

About this product

Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. It belongs to the group of claudins.Claudins, such as CLDN7, are involved in the formation of tight junctions between epithelial cells. Tight junctions restrict lateral diffusion of lipids and membrane proteins, and thereby physically define the border between the apical and basolateral compartments of epithelial cells. It is expressed in kidney, lung and prostate. Claudin-7 is down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions.

Specifications

Catalog number
M1412-2
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
CEPTR L2 antibody CEPTRL 2 antibody CEPTRL2 antibody Claudin 1 antibody Claudin 9 antibody Claudin-7 antibody Claudin1 antibody Claudin7 antibody Claudin9 antibody CLD7_HUMAN antibody CLDN 7 antibody CLDN-7 antibody CLDN7 antibody Clostridium perfringens enterotoxin receptor like 2 antibody CPETR L2 antibody CPETRL 2 antibody CPETRL2 antibody Hs.84359 antibody
Abbreviation
CLDN-7
Swiss Prot
O95471 Human, Q9Z261 Mouse, Q9Z1L1 Rat
Cellular Locus
Cell membrane, Basolateral cell membrane, Cell junction, tight junction.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Claudin 7 aa 162-211 / 211.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, IF-Tissue
Positive Control
SW480 cell lysate, MCF7 cell lysate, LNCaP cell lysate, Caco-2 cell lysate, A431 cell lysate, mouse colon tissue lysate, rat colon tissue lysate, PC-12, human kidney tissue, mouse colon tissue, rat colon tissue.
Concentration
2 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:100 ;IHC-P: 1:5,000 ;IF-Tissue: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 22 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Claudin 7 Mouse Monoclonal Antibody [6-G3]?

The catalog number for Claudin 7 Mouse Monoclonal Antibody [6-G3] is M1412-2.

What sizes are available for Claudin 7 Mouse Monoclonal Antibody [6-G3]?

Claudin 7 Mouse Monoclonal Antibody [6-G3] is available in the following size(s): 100 µL.

Is Claudin 7 Mouse Monoclonal Antibody [6-G3] in stock?

Claudin 7 Mouse Monoclonal Antibody [6-G3] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Claudin 7 Mouse Monoclonal Antibody [6-G3] used for?

Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. It belongs to the group of claudins.Claudins, such as CLDN7, are involved in the formation of tight junctions between epithelial cells. Tight junctions restrict lateral diffusion of lipids and membrane proteins, and thereby physical

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

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