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Product details

Desmin Mouse Monoclonal Antibody [3-F7]

Catalog number M1501-10

Price for M1501-10

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Size / count 100 µL

About this product

Desmin is one of the earliest protein markers for muscle tissue in embryogenesis as it is detected in the somites. Although it is present early in the development of muscle cells, it is only expressed at low levels, and increases as the cell nears terminal differentiation. Desmin is also important in muscle cell architecture and structure since it connects many components of the cytoplasm. Finally, desmin may be important in mitochondria function. Desmin-related myopathy (DRM or Desminopathy) is a subgroup of the myofibrillar myopathy diseases and is the result of a mutation in the gene that codes for desmin which prevents it from forming protein filaments, instead forming aggregates of desmin and other proteins throughout the cell. Recently, mutations were identified in patients suffered by an arrhythmogenic right ventricular cardiomyopathy (ARVC).

Specifications

Catalog number
M1501-10
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
CMD1I antibody CSM1 antibody CSM2 antibody DES antibody DESM_HUMAN antibody Desmin antibody FLJ12025 antibody FLJ39719 antibody FLJ41013 antibody FLJ41793 antibody Intermediate filament protein antibody OTTHUMP00000064865 antibody
Abbreviation
DES
Swiss Prot
P17661 Human, P31001 Mouse, P48675 Rat
Cellular Locus
Cytopasm, Nucleus, Cell membrane
Host
Mouse
Species Reactivity
Human, Mouse
Immunogen
Recombinant protein within human Desmin aa 300-470.
Isotype
IgG2b
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control
Rat heart tissue lysate, rat skeletal muscle tissue lysate, human skeletal muscle tissue lysate, human heart tissue lysate, D3, Hela, HepG2, human cervix tissue, human stomach cancer tissue, human uterus tissue.
Concentration
2 mg/mL
Dilution
WB: 1:2,000 ;IF-Cell: 1:200 ;IF-Tissue: 1:100 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 53 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Desmin Mouse Monoclonal Antibody [3-F7]?

The catalog number for Desmin Mouse Monoclonal Antibody [3-F7] is M1501-10.

What sizes are available for Desmin Mouse Monoclonal Antibody [3-F7]?

Desmin Mouse Monoclonal Antibody [3-F7] is available in the following size(s): 100 µL.

Is Desmin Mouse Monoclonal Antibody [3-F7] in stock?

Desmin Mouse Monoclonal Antibody [3-F7] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Desmin Mouse Monoclonal Antibody [3-F7] used for?

Desmin is one of the earliest protein markers for muscle tissue in embryogenesis as it is detected in the somites. Although it is present early in the development of muscle cells, it is only expressed at low levels, and increases as the cell nears terminal differentiation. Desmin is also important i

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

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