MASP2 Mouse Monoclonal Antibody [F3-4]

About this product

Mannan-binding lectin serine protease 2 also known as mannose-binding protein-associated serine protease 2 (MASP-2) is an enzyme that in humans is encoded by the MASP2 gene. MASP-2 involved in the complement system. MASP-2 is very similar to the C1s molecule, of the classical complement pathway, and they are thought to have a common evolutionary ancestor. When the carbohydrate-recognising heads of MBL bind to specifically arranged mannose residues on the surface of a pathogen, MASP-2 is activated to cleave complement components C4 and C2 into C4a, C4b, C2a, and C2b.

Specifications

Catalog number

M1501-11

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

Mannan binding lectin serine peptidase 2 antibody Mannan binding lectin serine protease 2 antibody Mannose binding protein associated serine protease 2 antibody MAP 19 antibody MAP19 antibody MASP 2 antibody MBL associated plasma protein of 19 kD antibody MBL associated serine protease 2 antibody Small MBL associated protein antibody sMAP antibody

Abbreviation

5'-dRP lyase Ku70,CTC75,CTCBF,Ku70,TLAA

Swiss Prot

O00187 Human

Cellular Locus

Secreted

Host

Mouse

Species Reactivity

Human

Immunogen

Synthetic peptide within human MASP2 aa 335-379/686.

Isotype

IgG2b

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB

Positive Control

Human serum

Concentration

2 mg/mL

Dilution

WB: 1:2,000-1:5,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: ~76kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

No