JAK2 Mouse Monoclonal Antibody [6-D3] — image 1 of 3

Product details

JAK2 Mouse Monoclonal Antibody [6-D3]

Catalog number M1501-8

Price for M1501-8

Size / count 100 µL

About this product

Janus kinase 2 (commonly called JAK2) is a non-receptor tyrosine kinase. It is a member of the Janus kinase family and has been implicated in signaling by members of the type II cytokine receptor family (e.g. interferon receptors), the GM-CSF receptor family (IL-3R, IL-5R and GM-CSF-R), the gp130 receptor family (e.g., IL-6R), and the single chain receptors (e.g. Epo-R, Tpo-R, GH-R, PRL-R). JAK2 signaling is activated downstream from the prolactin receptor. Jak - 2 kinase mutations were found to have a high correlation with abnormal heart defects in those of Southeast Asian descent carrying the PYFA gene. Mutations in JAK2 have been implicated in polycythemia vera, essential thrombocythemia, and myelofibrosis as well as other myeloproliferative disorders.

Specifications

Catalog number: M1501-8
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: JAK 2 antibody JAK-2 antibody JAK2 antibody JAK2_HUMAN antibody Janus Activating Kinase 2 antibody Janus kinase 2 (a protein tyrosine kinase) antibody Janus kinase 2 antibody JTK 10 antibody JTK10 antibody kinase Jak2 antibody OTTHUMP00000043260 antibody THCYT3 antibody Tyrosine protein kinase JAK2 antibody Tyrosine-protein kinase JAK2 antibody
Abbreviation: JAK-2
Swiss Prot: O60674 Human
Cellular Locus: Cytopasm, nucleus
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human JAK2 aa 883-1,132 / 1,132.
Isotype: IgG2b
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: A549 cell lysate, K-562 cell lysate, TF-1 cell lysate, Jurkat cell lysate, RAW264.7 cell lysate, C6 cell lysate, K-562, RAW264.7, human kidney tissue, human lung carcinoma tissue, mouse kidney tissue, rat kidney tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:2,000 ;IF-Cell: 1:50-1:100 ;IHC-P: 1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 130 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for JAK2 Mouse Monoclonal Antibody [6-D3]?

The catalog number for JAK2 Mouse Monoclonal Antibody [6-D3] is M1501-8.

What sizes are available for JAK2 Mouse Monoclonal Antibody [6-D3]?

JAK2 Mouse Monoclonal Antibody [6-D3] is available in the following size(s): 100 µL.

Is JAK2 Mouse Monoclonal Antibody [6-D3] in stock?

JAK2 Mouse Monoclonal Antibody [6-D3] is currently made to order / not held in immediate stock. Contact us for lead time.

What is JAK2 Mouse Monoclonal Antibody [6-D3] used for?

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.