SHP1 Mouse Monoclonal Antibody [B5-A4] — image 1 of 3

Product details

SHP1 Mouse Monoclonal Antibody [B5-A4]

Catalog number M1505-4

Price for M1505-4

Size / count 100 µL

About this product

Tyrosine-protein phosphatase non-receptor type 6, also known as Src homology region 2 domain-containing phosphatase-1 (SHP-1), is an enzyme that in humans is encoded by the PTPN6 gene. SHP1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. SHP-1 gene has two promoters - P-1, active in epithelial cells, and P-2, active in hemopoietic cells. In addition the expression of SHP-1 is low in epithelial cells and high in hemopoetic cells. SHP-1 level in epithelial cells increases and in hematopoetic cells decreases in cancer.

Specifications

Catalog number: M1505-4
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 70Z-SHP antibody EC 3.1.3.48 antibody HCP antibody HCPH antibody Hematopoietic cell phosphatase antibody Hematopoietic cell protein tyrosine phosphatase antibody Hematopoietic cell protein-tyrosine phosphatase antibody HPTP1C antibody Protein tyrosine phosphatase 1C antibody Protein tyrosine phosphatase non receptor type 6 antibody Protein tyrosine phosphatase SHP1 antibody Protein-tyrosine phosphatase 1C antibody protein-tyrosine phosphatase SHP 1 antibody Protein-tyrosine phosphatase SHP-1 antibody PTN6_HUMAN antibody PTP 1C antibody PTP-1C antibody PTP1C antibody Ptpn6 antibody SH PTP 1 antibody SH PTP1 antibody SH-PTP1 antibody SHP 1 antibody SHP 1L antibody SHP1 antibody SHP1L antibody tyrosine protein phosphatase non receptor type 6 antibody Tyrosine-protein phosphatase non-receptor type 6 antibody
Abbreviation: PTP-1C
Swiss Prot: P29350 Human, P29351 Mouse
Cellular Locus: Cytoplasm, nucleus
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human SHP1 aa 400-590/595.
Isotype: IgG2b
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: Mouse tonsil, human tonsil, mouse lymphoid tissue
Concentration: 2 mg/mL
Dilution: WB: 1:500-1:1,000;IHC-P: 1:200;IF-Cell: 1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size:68kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for SHP1 Mouse Monoclonal Antibody [B5-A4]?

The catalog number for SHP1 Mouse Monoclonal Antibody [B5-A4] is M1505-4.

What sizes are available for SHP1 Mouse Monoclonal Antibody [B5-A4]?

SHP1 Mouse Monoclonal Antibody [B5-A4] is available in the following size(s): 100 µL.

Is SHP1 Mouse Monoclonal Antibody [B5-A4] in stock?

SHP1 Mouse Monoclonal Antibody [B5-A4] is currently made to order / not held in immediate stock. Contact us for lead time.

What is SHP1 Mouse Monoclonal Antibody [B5-A4] used for?

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.