Cdk4 Mouse Monoclonal Antibody [5-C3-G3] — image 1 of 3

Product details

Cdk4 Mouse Monoclonal Antibody [5-C3-G3]

Catalog number M1505-5

Price for M1505-5

Size / count 100 µL

About this product

Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression . Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Several Cdk proteins have been identified, including Cdk2-Cdk8, PCTAIRE-1-PCTAIRE-3, PITALRE and PITSLRE. Cdk4, in complex with D-type cyclins, is thought to regulate cell growth during the G1 phase of the cell cycle. This association with a D-type cyclin upregulates Cdk4 activity, whereas binding to the Cdk inhibitor p16 downregulates Cdk4 activity. Activation of the Cdk4-cyclin complexes requires phosphorylation on a single threonyl residue of Cdk4, catalyzed by a Cdk-activating protein (CAK).

Specifications

Catalog number: M1505-5
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Cdk 4 antibody cdk4 antibody CDK4 protein antibody CDK4_HUMAN antibody Cell division kinase 4 antibody Cell division protein kinase 4 antibody CMM 3 antibody CMM3 antibody Crk3 antibody Cyclin dependent kinase 4 antibody Cyclin-dependent kinase 4 antibody Melanoma cutaneous malignant 3 antibody MGC14458 antibody p34 cdk4 antibody PSK J3 antibody PSK-J3 antibody
Abbreviation: CDK4
Swiss Prot: P11802 Human, P30285 Mouse
Cellular Locus: Cytoplasm, Nucleus, Nucleus membrane.
Host: Mouse
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within human Cdk4 aa 80-303/303.
Isotype: IgG2c
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P
Positive Control: A549 cell lysate, 293T cell lysate, HeLa cell lysate, MCF7 cell lysate, K-562 cell lysate, mouse lung tissue lysate, human breast cancer tissue, human stomach cancer tissue, human thyroid cancer tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:500-1:5,000 ;IHC-P: 1:200-1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 34 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Cdk4 Mouse Monoclonal Antibody [5-C3-G3]?

The catalog number for Cdk4 Mouse Monoclonal Antibody [5-C3-G3] is M1505-5.

What sizes are available for Cdk4 Mouse Monoclonal Antibody [5-C3-G3]?

Cdk4 Mouse Monoclonal Antibody [5-C3-G3] is available in the following size(s): 100 µL.

Is Cdk4 Mouse Monoclonal Antibody [5-C3-G3] in stock?

Cdk4 Mouse Monoclonal Antibody [5-C3-G3] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cdk4 Mouse Monoclonal Antibody [5-C3-G3] used for?

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.