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Product details

ICAM1 Mouse Monoclonal Antibody [F11-A4]

Catalog number M1505-7

Price for M1505-7

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Size / count 100 µL

About this product

ICAM-1 is a member of the immunoglobulin superfamily, the superfamily of proteins including antibodies and T-cell receptors. The structure of ICAM-1 is characterized by heavy glycosylation, and the protein’s extracellular domain is composed of multiple loops created by disulfide bridges within the protein. ICAM-1 can be induced by interleukin-1 (IL-1) and tumor necrosis factor (TNF) and is expressed by the vascular endothelium, macrophages, and lymphocytes. ICAM-1 is a ligand for LFA-1 (integrin), a receptor found on leukocytes. More recently, ICAM-1 has been characterized as a site for the cellular entry of human rhinovirus. ICAM-1 and soluble ICAM-1 have antagonistic effects on the tight junctions forming the blood-testis barrier, thus playing a major role in spermatogenesis. ICAM-1 has been implicated in subarachnoid hemorrhage (SAH). Levels of ICAM-1 are shown to be significantly elevated in patients with SAH over control subjects in many studies.

Specifications

Catalog number
M1505-7
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Antigen identified by monoclonal antibody BB2 antibody BB 2 antibody BB2 antibody CD 54 antibody CD_antigen=CD54 antibody CD54 antibody Cell surface glycoprotein P3.58 antibody Human rhinovirus receptor antibody ICAM 1 antibody ICAM-1 antibody ICAM1 antibody ICAM1_HUMAN antibody intercellular adhesion molecule 1 (CD54), human rhinovirus receptor antibody Intercellular adhesion molecule 1 antibody Major group rhinovirus receptor antibody MALA 2 antibody MALA2 antibody MyD 10 antibody MyD10 antibody P3.58 antibody Surface antigen of activated B cells, BB1 antibody
Abbreviation
ICAM-1
Swiss Prot
P05362 Human
Cellular Locus
Membrane.
Host
Mouse
Species Reactivity
Human
Immunogen
Synthetic peptide within Human ICAM1 aa 483-532 / 532.
Isotype
IgG2a/IgG2c
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
HUVEC, HepG2
Concentration
2 mg/mL
Dilution
WB: 1:2,000-1:5,000;IF-Cell: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 58 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for ICAM1 Mouse Monoclonal Antibody [F11-A4]?

The catalog number for ICAM1 Mouse Monoclonal Antibody [F11-A4] is M1505-7.

What sizes are available for ICAM1 Mouse Monoclonal Antibody [F11-A4]?

ICAM1 Mouse Monoclonal Antibody [F11-A4] is available in the following size(s): 100 µL.

Is ICAM1 Mouse Monoclonal Antibody [F11-A4] in stock?

ICAM1 Mouse Monoclonal Antibody [F11-A4] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ICAM1 Mouse Monoclonal Antibody [F11-A4] used for?

ICAM-1 is a member of the immunoglobulin superfamily, the superfamily of proteins including antibodies and T-cell receptors. The structure of ICAM-1 is characterized by heavy glycosylation, and the protein’s extracellular domain is composed of multiple loops created by disulfide bridges within the p

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

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