ALDH2 Mouse Monoclonal Antibody [E4-D10] — image 1 of 3

Product details

ALDH2 Mouse Monoclonal Antibody [E4-D10]

Catalog number M1509-1

Price for M1509-1

Size / count 100 µL

About this product

Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde; lipid peroxidation; and metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1); aldehyde dehydrogenase family 1 member A1; aldehyde dehydrogenase cytosolic; ALDHII; ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). The major liver isoform ALDH1 localizes to cytosolic space, while ALDH2 localizzes to the mitochondria. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH2 is present in most Caucasians, yet is absent in 50% of Asians. The absence of this enzyme has been linked to alcohol intolerance; and thusly, a reduced risk for alcoholism-related liver disease.

Specifications

Catalog number: M1509-1
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Acetaldehyde dehydrogenase 2 antibody Aldehyde dehydrogenase 2 family (mitochondrial) antibody Aldehyde dehydrogenase 2 family antibody Aldehyde dehydrogenase mitochondrial antibody Aldehyde dehydrogenase, mitochondrial antibody ALDH 2 antibody ALDH class 2 antibody ALDH E2 antibody ALDH-E2 antibody Aldh2 antibody ALDH2_HUMAN antibody ALDHI antibody ALDM antibody Liver mitochondrial ALDH antibody MGC1806 antibody Mitochondrial aldehyde dehydrogenase 2 antibody MS767 antibody Nucleus encoded mitochondrial aldehyde dehydrogenase 2 antibody
Abbreviation: ALDH2
Swiss Prot: P05091 Human, P47738 Mouse, P11884 Rat
Cellular Locus: Mitochondrion matrix.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human ALDH2 aa 468-517 / 517.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control: HepG2 cell lysate, A549 cell lysate, NIH/3T3 cell lysate, SK-Br-3, HeLa, human lung cancer tissue, human liver cancer tissue, human colon cancer tissue, human gastric cancer tissue, mouse colon tissue, mouse stomach tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:1,000-1:5,000 ;IF-Cell: 1:100 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 56 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for ALDH2 Mouse Monoclonal Antibody [E4-D10]?

The catalog number for ALDH2 Mouse Monoclonal Antibody [E4-D10] is M1509-1.

What sizes are available for ALDH2 Mouse Monoclonal Antibody [E4-D10]?

ALDH2 Mouse Monoclonal Antibody [E4-D10] is available in the following size(s): 100 µL.

Is ALDH2 Mouse Monoclonal Antibody [E4-D10] in stock?

ALDH2 Mouse Monoclonal Antibody [E4-D10] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ALDH2 Mouse Monoclonal Antibody [E4-D10] used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.