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Product details

Fibrinogen Mouse Monoclonal Antibody [D5-B3]

Catalog number M1510-11

Price for M1510-11

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Size / count 100 µL

About this product

The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: a, b and g. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.

Specifications

Catalog number
M1510-11
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
FGA antibody Fib2 antibody FIBA_HUMAN antibody Fibrinogen A alpha polypeptide antibody Fibrinogen alpha chain antibody Fibrinogen B alpha polypeptide antibody Fibrinogen beta chain antibody Fibrinogen G alpha polypeptide antibody Fibrinogen gamma chain antibody fibrinogen, B beta polypeptide antibody fibrinogen, G gamma polypeptide antibody fibrinogen, gamma polypeptide antibody Fibrinogen--alpha -polypeptide chain antibody Fibrinogen--beta -polypeptide chain antibody Fibrinogen--gamma-polypeptide chain antibody
Abbreviation
FGA
Swiss Prot
P02671 Human, P02675 Human, P02679 Human
Cellular Locus
Secreted.
Host
Mouse
Species Reactivity
Human
Immunogen
native protein.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
IHC-P, WB
Positive Control
HepG2 cell lysates, human liver tissue, human placenta tissue.
Concentration
2 mg/mL
Dilution
IHC-P:1:50-1:200 ;WB: 1:500-1:2000
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 95/56/52 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Fibrinogen Mouse Monoclonal Antibody [D5-B3]?

The catalog number for Fibrinogen Mouse Monoclonal Antibody [D5-B3] is M1510-11.

What sizes are available for Fibrinogen Mouse Monoclonal Antibody [D5-B3]?

Fibrinogen Mouse Monoclonal Antibody [D5-B3] is available in the following size(s): 100 µL.

Is Fibrinogen Mouse Monoclonal Antibody [D5-B3] in stock?

Fibrinogen Mouse Monoclonal Antibody [D5-B3] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Fibrinogen Mouse Monoclonal Antibody [D5-B3] used for?

The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: a, b and g. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythroc

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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