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Product details

Fibrinogen Mouse Monoclonal Antibody [11-B3-D8]

Catalog number M1510-12

Price for M1510-12

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Size / count 100 µL

About this product

The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: a, b and g. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.

Specifications

Catalog number
M1510-12
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
FGA antibody Fib2 antibody FIBA_HUMAN antibody Fibrinogen A alpha polypeptide antibody Fibrinogen alpha chain antibody Fibrinogen B alpha polypeptide antibody Fibrinogen beta chain antibody Fibrinogen G alpha polypeptide antibody Fibrinogen gamma chain antibody fibrinogen, B beta polypeptide antibody fibrinogen, G gamma polypeptide antibody fibrinogen, gamma polypeptide antibody Fibrinogen--alpha -polypeptide chain antibody Fibrinogen--beta -polypeptide chain antibody Fibrinogen--gamma-polypeptide chain antibody
Abbreviation
FGA,FGB,FGG
Swiss Prot
P02671 Human, P02675 Human, P02679 Human
Cellular Locus
Secreted.
Host
Mouse
Species Reactivity
Human
Immunogen
Native protein
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P, ELISA
Concentration
2 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:50-1:200 ;ELISA: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 95/56/52 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Fibrinogen Mouse Monoclonal Antibody [11-B3-D8]?

The catalog number for Fibrinogen Mouse Monoclonal Antibody [11-B3-D8] is M1510-12.

What sizes are available for Fibrinogen Mouse Monoclonal Antibody [11-B3-D8]?

Fibrinogen Mouse Monoclonal Antibody [11-B3-D8] is available in the following size(s): 100 µL.

Is Fibrinogen Mouse Monoclonal Antibody [11-B3-D8] in stock?

Fibrinogen Mouse Monoclonal Antibody [11-B3-D8] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Fibrinogen Mouse Monoclonal Antibody [11-B3-D8] used for?

The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: a, b and g. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythroc

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

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