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Product details

Alpha-2-macroglobulin Mouse Monoclonal Antibody [A5-A9]

Catalog number M1510-22

Price for M1510-22

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Size / count 100 µL

About this product

Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Specifications

Catalog number
M1510-22
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
A2m antibody A2MG_HUMAN antibody Alpha 2 M antibody Alpha 2M antibody Alpha-2-M antibody Alpha-2-macroglobulin antibody C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 antibody CPAMD5 antibody DKFZp779B086 antibody FWP007 antibody S863 7 antibody
Abbreviation
Alpha-2-M
Swiss Prot
P01023 Human
Cellular Locus
Secreted.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within human Alpha-2-macroglobulin aa 950-1200.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, ELISA
Positive Control
LOVO cell lysates, LO2 cell lysates, Hela, HepG2, human liver tissue, human uterus tissue.
Concentration
2 mg/mL
Dilution
WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:100-1:500 ;ELISA: 1:1,000-1:10,000
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 163 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Alpha-2-macroglobulin Mouse Monoclonal Antibody [A5-A9]?

The catalog number for Alpha-2-macroglobulin Mouse Monoclonal Antibody [A5-A9] is M1510-22.

What sizes are available for Alpha-2-macroglobulin Mouse Monoclonal Antibody [A5-A9]?

Alpha-2-macroglobulin Mouse Monoclonal Antibody [A5-A9] is available in the following size(s): 100 µL.

Is Alpha-2-macroglobulin Mouse Monoclonal Antibody [A5-A9] in stock?

Alpha-2-macroglobulin Mouse Monoclonal Antibody [A5-A9] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Alpha-2-macroglobulin Mouse Monoclonal Antibody [A5-A9] used for?

Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the pro

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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