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Product details

Alpha-2-macroglobulin Mouse Monoclonal Antibody [8-B10]

Catalog number M1510-23

Price for M1510-23

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Size / count 100 µL

About this product

Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Specifications

Catalog number
M1510-23
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
A2m antibody A2MG_HUMAN antibody Alpha 2 M antibody Alpha 2M antibody Alpha-2-M antibody Alpha-2-macroglobulin antibody C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 antibody CPAMD5 antibody DKFZp779B086 antibody FWP007 antibody S863 7 antibody
Abbreviation
Alpha-2-M
Swiss Prot
P01023 Human, Q61838 Mouse, P06238 Rat
Cellular Locus
Secreted.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human Alpha-2-macroglobulin aa 950-1200.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
ELISA, IF-Cell, IHC-P
Positive Control
H22, rat uterus tissue, human liver tissue, mouse liver tissue.
Concentration
2 mg/mL
Dilution
ELISA:1:1,000-1:5,000;IF-Cell:1:50;IHC-P:1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 163 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Alpha-2-macroglobulin Mouse Monoclonal Antibody [8-B10]?

The catalog number for Alpha-2-macroglobulin Mouse Monoclonal Antibody [8-B10] is M1510-23.

What sizes are available for Alpha-2-macroglobulin Mouse Monoclonal Antibody [8-B10]?

Alpha-2-macroglobulin Mouse Monoclonal Antibody [8-B10] is available in the following size(s): 100 µL.

Is Alpha-2-macroglobulin Mouse Monoclonal Antibody [8-B10] in stock?

Alpha-2-macroglobulin Mouse Monoclonal Antibody [8-B10] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Alpha-2-macroglobulin Mouse Monoclonal Antibody [8-B10] used for?

Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the pro

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

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