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Product details

Haptoglobin Mouse Monoclonal Antibody [5-D3]

Catalog number M1510-37

Price for M1510-37

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Size / count 100 µL

About this product

As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.

Specifications

Catalog number
M1510-37
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Binding peptide antibody BP antibody Haptoglobin alpha chain antibody Haptoglobin alpha (1S) beta antibody Haptoglobin alpha (2FS) beta antibody Haptoglobin beta chain antibody Haptoglobin, alpha polypeptide antibody Haptoglobin, beta polypeptide antibody HP antibody HP2 ALPHA2 antibody HP2ALPHA2 antibody HPA1S antibody HPT antibody HPT_HUMAN antibody MGC111141 antibody Zonulin antibody
Abbreviation
HP
Swiss Prot
P00738 Human
Cellular Locus
Extracellular region, secreted.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Native Human Haptoglobin protein.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
Human lung tissue lysate, human liver tissue lysate, HepG2, Hela, rat liver tissue, mouse liver tissue, human liver tissue, human lung cancer tissue.
Concentration
2 mg/mL
Dilution
WB: 1:500-1:2,000;IF-Cell: 1:100-1:500;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 45 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Haptoglobin Mouse Monoclonal Antibody [5-D3]?

The catalog number for Haptoglobin Mouse Monoclonal Antibody [5-D3] is M1510-37.

What sizes are available for Haptoglobin Mouse Monoclonal Antibody [5-D3]?

Haptoglobin Mouse Monoclonal Antibody [5-D3] is available in the following size(s): 100 µL.

Is Haptoglobin Mouse Monoclonal Antibody [5-D3] in stock?

Haptoglobin Mouse Monoclonal Antibody [5-D3] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Haptoglobin Mouse Monoclonal Antibody [5-D3] used for?

As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has ant

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

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