Haptoglobin Mouse Monoclonal Antibody [5-D3]

Catalog number M1510-38

Price for M1510-38

Size / count 100 µL

About this product

Haptoglobin (abbreviated as Hp) is the protein that in humans is encoded by the HP gene. In blood plasma, haptoglobin binds with high affinity to free hemoglobin released from erythrocytes, and thereby inhibits its deleterious oxidative activity. Hemoglobin that has been released into the blood plasma by damaged red blood cells has harmful effects. The HP gene encodes a preproprotein that is processed to yield both alpha and beta chains, which subsequently combines as a tetramer to produce haptoglobin. Haptoglobin functions to bind the free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. The cellular receptor target of Hp is the monocyte/macrophage scavenger receptor, CD163. Following Hb-Hp binding to CD163, cellular internalization of the complex leads to globin and heme metabolism, which is followed by adaptive changes in antioxidant and iron metabolism pathways and macrophage phenotype polarization.

Specifications

Catalog number: M1510-38
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Binding peptide antibody BP antibody Haptoglobin alpha chain antibody Haptoglobin alpha (1S) beta antibody Haptoglobin alpha (2FS) beta antibody Haptoglobin beta chain antibody Haptoglobin, alpha polypeptide antibody Haptoglobin, beta polypeptide antibody HP antibody HP2 ALPHA2 antibody HP2ALPHA2 antibody HPA1S antibody HPT antibody HPT_HUMAN antibody MGC111141 antibody Zonulin antibody
Abbreviation: HP
Swiss Prot: P00738 Human
Cellular Locus: Secreted.
Host: Mouse
Species Reactivity: Human
Immunogen: Native protein
Isotype: IgM
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P, ELISA
Concentration: 2 mg/mL
Dilution: WB: 1:500 ;IHC-P: 1:50-1:200 ;ELISA: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 45 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Haptoglobin Mouse Monoclonal Antibody [5-D3]?

The catalog number for Haptoglobin Mouse Monoclonal Antibody [5-D3] is M1510-38.

What sizes are available for Haptoglobin Mouse Monoclonal Antibody [5-D3]?

Haptoglobin Mouse Monoclonal Antibody [5-D3] is available in the following size(s): 100 µL.

Is Haptoglobin Mouse Monoclonal Antibody [5-D3] in stock?

Haptoglobin Mouse Monoclonal Antibody [5-D3] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Haptoglobin Mouse Monoclonal Antibody [5-D3] used for?

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.