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Product details

PTP1B Mouse Monoclonal Antibody [D0-C7]

Catalog number M1511-7

Price for M1511-7

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Size / count 100 µL

About this product

The phosphorylation of proteins at tyrosine residues has long been recognized as an important regulatory component of signal transduction. This is a reversible process, involving both enzymes that phosphorylate proteins on tyrosine residues as well as a rapidly expanding family of protein tyrosine phosphatases. These latter enzymes bear little resemblance to either the protein serine and protein threonine phosphatases or to the acid and alkaline phosphatases. In most tissues, the major PTPase is a vanadate- and molybdate-sensitive protein. On the basis of sequence analysis, PTP1B (PTPase 1B) expressed in human placenta exhibits similarities both with the common leukocyte antigen (CD45) and with LAR, a homolog of the neural adhesion molecule (NCAM). PTP1B is synthesized as a 435 amino acid precursor protein which is cleaved to generate the active 321 amino acid enzyme.

Specifications

Catalog number
M1511-7
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
PTP1B antibody Non receptor tyrosine phosphatase 1 antibody Protein phosphotyrosylphosphatase 1B antibody Protein tyrosine phosphatase 1B antibody Protein tyrosine phosphatase non receptor type 1 antibody Protein tyrosine phosphatase placental antibody Protein-tyrosine phosphatase 1B antibody PTN1_HUMAN antibody PTP 1B antibody PTP-1B antibody PTPN 1 antibody PTPN1 antibody Tyrosine protein phosphatase non receptor type 1 antibody Tyrosine-protein phosphatase non-receptor type 1 antibody
Abbreviation
PTP-1B, PTPN1, PTP1B
Swiss Prot
P18031 Human, P35821 Mouse, P20417 Rat
Cellular Locus
Endoplasmic reticulum membrane
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human PTP1B aa 1-250.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, FC
Positive Control
A431 cell lysate, Hela cell lysate, A549 cell lysate, HepG2 cell lysate, RAW264.7 cell lysate, PC-12 cell lysate, C6 cell lysate, Hela, A549, HepG2, Jurkat.
Concentration
2 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IF-Cell: 1:100-1:500 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 50 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for PTP1B Mouse Monoclonal Antibody [D0-C7]?

The catalog number for PTP1B Mouse Monoclonal Antibody [D0-C7] is M1511-7.

What sizes are available for PTP1B Mouse Monoclonal Antibody [D0-C7]?

PTP1B Mouse Monoclonal Antibody [D0-C7] is available in the following size(s): 100 µL.

Is PTP1B Mouse Monoclonal Antibody [D0-C7] in stock?

PTP1B Mouse Monoclonal Antibody [D0-C7] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PTP1B Mouse Monoclonal Antibody [D0-C7] used for?

The phosphorylation of proteins at tyrosine residues has long been recognized as an important regulatory component of signal transduction. This is a reversible process, involving both enzymes that phosphorylate proteins on tyrosine residues as well as a rapidly expanding family of protein tyrosine p

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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