PP2A (alpha+beta) Mouse Monoclonal Antibody [A0-G7] — image 1 of 3

Product details

PP2A (alpha+beta) Mouse Monoclonal Antibody [A0-G7]

Catalog number M1603-4

Price for M1603-4

Size / count 100 µL

About this product

PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Dephosphorylates SV40 large T antigen, preferentially on serine residues 120, 123, 677, and perhaps 679. The C subunit was most active, followed by the AC form, which was more active than the ABC form, and activity of all three forms was strongly stimulated by manganese, and to a lesser extent by magnesium. Dephosphorylation by the AC form, but not C or ABC form is inhibited by small T antigen. Activates RAF1 by dephosphorylating it at 'Ser-259'.

Specifications

Catalog number: M1603-4
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: PP2A A antibody PP2A alpha antibody PP2A B antibody PP2A beta antibody PP2A-alpha antibody PP2AA_HUMAN antibody PP2Ac antibody PP2CB antibody PPP2CA antibody PPP2CB antibody Protein phosphatase 2 catalytic subunit alpha isoform antibody Protein phosphatase 2 catalytic subunit beta isoform antibody Replication protein C antibody RP C antibody RP-C antibody Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform antibody Serine/threonine protein phosphatase 2A catalytic subunit beta isoform antibody Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody
Abbreviation: PP2A-alpha, RP-C, PP2A-beta, PPP2CB, PPP2CA
Swiss Prot: P62714 Human, P67775 Human
Cellular Locus: Cytoplasm. Nucleus.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human PP2A (alpha+beta) aa 260-309 / 309.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IF-Cell
Positive Control: A431 cell lysate, Hela, MCF-7, SHG-44.
Concentration: 2 mg/mL
Dilution: WB: 1:2,000-1:5,000 ;IF-Cell: 1:100-1:500 ;FC: 1:50-1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 35 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for PP2A (alpha+beta) Mouse Monoclonal Antibody [A0-G7]?

The catalog number for PP2A (alpha+beta) Mouse Monoclonal Antibody [A0-G7] is M1603-4.

What sizes are available for PP2A (alpha+beta) Mouse Monoclonal Antibody [A0-G7]?

PP2A (alpha+beta) Mouse Monoclonal Antibody [A0-G7] is available in the following size(s): 100 µL.

Is PP2A (alpha+beta) Mouse Monoclonal Antibody [A0-G7] in stock?

PP2A (alpha+beta) Mouse Monoclonal Antibody [A0-G7] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PP2A (alpha+beta) Mouse Monoclonal Antibody [A0-G7] used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.