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Product details

GRP94 Mouse Monoclonal Antibody [F1-D10-G3]

Catalog number M1701-12

Price for M1701-12

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Size / count 100 µL

About this product

The human HSP 90 family includes 17 genes that fall into four classes: HSP90AA, HSP90AB, HSP90B and TRAP. HSP 90 family members guide the normal folding, intracellular disposition and Proteolytic turnover of many key regulators of cell growth, differentiation and survival. HSP 90α, also designated HSP90A, HSP 86 and LPS-associated protein 2 (LAP2), is a cytosolic enhancer of inducible nitric-oxide synthase (iNOS), with chaperone activity that is important for the transcriptional activity of p53. HSP 90β, also designated HSP90B, HSP 84 and HSPC2, is a cytosolic protein that participates in signaling pathways with PKC e to protect cells from external damage, particularly in heat shock-mediated events. GRP 94, also known as tumor rejection antigen 1 (TRA1), ECGP and GP96, localizes to the ER, is highly expressed in BGC-823 human gastric carcinoma cells and is upregulated in human endothelial cells in response to hypoxia by HIF-1.

Specifications

Catalog number
M1701-12
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
94 kDa glucose regulated protein antibody 94 kDa glucose-regulated protein antibody ECGP antibody Endoplasmin antibody Endothelial cell (HBMEC) glycoprotein antibody ENPL_HUMAN antibody Glucose regulated protein 94kDa antibody gp96 antibody gp96 homolog antibody GRP 94 antibody GRP-94 antibody Heat shock protein 90 kDa beta member 1 antibody heat shock protein 90kDa beta (Grp94), member 1 antibody Heat shock protein, 90 kDa, beta, 1 antibody HSP90B1 antibody Stress inducible tumor rejection antigen GP96 antibody TRA1 antibody tumor rejection antigen (gp96) 1 antibody Tumor rejection antigen 1 antibody Tumor rejection antigen gp96 antibody Tumor rejection antigen-1 (gp96) antibody
Abbreviation
GRP-94, HSP90B1, GRP94, TRA1
Swiss Prot
P14625 Human, P08113 Mouse, Q66HD0 Rat
Cellular Locus
Endoplasmic reticulum lumen, melanosome.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human GRP94 aa 201-400 / 803.
Isotype
IgM
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
HepG2 cell lysate, HeLa cell lysate, human brain tissue lysate, NIH/3T3 cell lysate, mouse placenta tissue lysate, mouse brain tissue lysate, PC-12 cell lysate, rat placenta tissue lysate, rat brain tissue lysate, NIH-3T3, human liver cancer tissue, human kidney tissue, mouse testis tissue, mouse brain tissue.
Concentration
2 mg/mL
Dilution
WB: 1:1,000-1:10,000 ;IF-Cell: 1:50 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 94 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for GRP94 Mouse Monoclonal Antibody [F1-D10-G3]?

The catalog number for GRP94 Mouse Monoclonal Antibody [F1-D10-G3] is M1701-12.

What sizes are available for GRP94 Mouse Monoclonal Antibody [F1-D10-G3]?

GRP94 Mouse Monoclonal Antibody [F1-D10-G3] is available in the following size(s): 100 µL.

Is GRP94 Mouse Monoclonal Antibody [F1-D10-G3] in stock?

GRP94 Mouse Monoclonal Antibody [F1-D10-G3] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GRP94 Mouse Monoclonal Antibody [F1-D10-G3] used for?

The human HSP 90 family includes 17 genes that fall into four classes: HSP90AA, HSP90AB, HSP90B and TRAP. HSP 90 family members guide the normal folding, intracellular disposition and Proteolytic turnover of many key regulators of cell growth, differentiation and survival. HSP 90α, also designated H

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

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