Cytochrome C Mouse Monoclonal Antibody [10-E11-G2] — image 1 of 3

Product details

Cytochrome C Mouse Monoclonal Antibody [10-E11-G2]

Catalog number M1701-9

Price for M1701-9

Size / count 100 µL

About this product

Cytochrome c is a well characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial intermembrane space. More recent studies have identifed cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is translocated from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Specifications

Catalog number: M1701-9
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CYC antibody CYC_HUMAN antibody CYCS antibody Cytochrome c antibody Cytochrome c somatic antibody HCS antibody THC4 antibody
Abbreviation: CYCS, CYC
Swiss Prot: P99999 Human, P62897 Mouse, P62898 Rat
Cellular Locus: Mitochondrion.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human Cytochrome C aa 2-60.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P, IF-Cell
Positive Control: Mouse brain tissue lysate, Mouse kidney tissue lysate, Hela, HepG2, MCF-7, human liver tissue, human spleen tissue, human kidney tissue, mouse heart tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:200-1:500 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:600
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 12 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Cytochrome C Mouse Monoclonal Antibody [10-E11-G2]?

The catalog number for Cytochrome C Mouse Monoclonal Antibody [10-E11-G2] is M1701-9.

What sizes are available for Cytochrome C Mouse Monoclonal Antibody [10-E11-G2]?

Cytochrome C Mouse Monoclonal Antibody [10-E11-G2] is available in the following size(s): 100 µL.

Is Cytochrome C Mouse Monoclonal Antibody [10-E11-G2] in stock?

Cytochrome C Mouse Monoclonal Antibody [10-E11-G2] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cytochrome C Mouse Monoclonal Antibody [10-E11-G2] used for?

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.