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Product details

Histone H3 Rabbit Polyclonal Antibody

Catalog number R1105-1

Price for R1105-1

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Size / count 100 µL

About this product

The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Histone H3 is primarily acetylated at Lys9, 14, 18, 23, 27, and 56. Acetylation of H3 at Lys9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. This Antibody detects endogenous levels of total histone H3 protein, and does not cross-react with other histones.

Specifications

Catalog number
R1105-1
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
H3 histone family, member A antibody H3/A antibody H31_HUMAN antibody H3FA antibody Hist1h3a antibody HIST1H3B antibody HIST1H3C antibody HIST1H3D antibody HIST1H3E antibody HIST1H3F antibody HIST1H3G antibody HIST1H3H antibody HIST1H3I antibody HIST1H3J antibody histone 1, H3a antibody Histone cluster 1, H3a antibody Histone H3.1 antibody Histone H3/a antibody Histone H3/b antibody Histone H3/c antibody Histone H3/d antibody Histone H3/f antibody Histone H3/h antibody Histone H3/i antibody Histone H3/j antibody Histone H3/k antibody Histone H3/l antibody
Abbreviation
HIST1H3A
Swiss Prot
P68431 Human, P68433 Mouse, Q6LED0 Rat
Cellular Locus
Cell nucleus
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human Histone H3 aa 1-50.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB
Positive Control
HepG2, NIH/3T3, Rat liver
Concentration
1 mg/mL
Dilution
WB: 1:1,000~1:2,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 15 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Histone H3 Rabbit Polyclonal Antibody?

The catalog number for Histone H3 Rabbit Polyclonal Antibody is R1105-1.

What sizes are available for Histone H3 Rabbit Polyclonal Antibody?

Histone H3 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Histone H3 Rabbit Polyclonal Antibody in stock?

Histone H3 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Histone H3 Rabbit Polyclonal Antibody used for?

The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regula

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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