HMGB1 Rabbit Polyclonal Antibody — image 1 of 3

Product details

HMGB1 Rabbit Polyclonal Antibody

Catalog number R1309-12

Price for R1309-12

Size / count 100 µL

About this product

Like the histones, HMGB1, also known as high-mobility group protein 1 (HMG-1) is among the most important chromatin proteins. In the nucleus HMGB1 interacts with nucleosomes, transcription factors, and histones. This nuclear protein organizes the DNA and regulates transcription. After binding, HMGB1 bends DNA, which facilitates the binding of other proteins. HMGB1 is secreted by immune cells (like macrophages, monocytes and dendritic cells) through leaderless secretory pathway. Activated macrophages and monocytes secrete HMGB1 as a cytokine mediator of Inflammation. In recent research, HMGB1 has been reported as a novel biomarker for human ovarian cancer.

Specifications

Catalog number: R1309-12
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Amphoterin antibody Chromosomal protein, nonhistone, HMG1 antibody DKFZp686A04236 antibody High mobility group 1 antibody High mobility group box 1 antibody High mobility group protein 1 antibody High mobility group protein B1 antibody high-mobility group (nonhistone chromosomal) protein 1 antibody HMG-1 antibody HMG1 antibody HMG3 antibody HMGB 1 antibody HMGB1 antibody HMGB1_HUMAN antibody NONHISTONE CHROMOSOMAL PROTEIN HMG1 antibody SBP 2 antibody Sulfoglucuronyl carbohydrate binding protein antibody
Abbreviation: HMG-1
Swiss Prot: P09429 Human
Cellular Locus: Nucleus, Cell membrane, Chromosome, Cytoplasm, Endoplasmic reticulum, Endosome, Membrane, Secreted.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within N-terminal human HMGB1.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: Wild-type Raw264.7 whole cell lysate, MCF-7 cell lysate, PC12 cell lysate, F9 cell lysate, Hela, mouse spleen tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000;IF-Cell: 1:200-1:500;IHC-P: 1:200;FC: 1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 25 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for HMGB1 Rabbit Polyclonal Antibody?

The catalog number for HMGB1 Rabbit Polyclonal Antibody is R1309-12.

What sizes are available for HMGB1 Rabbit Polyclonal Antibody?

HMGB1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is HMGB1 Rabbit Polyclonal Antibody in stock?

HMGB1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is HMGB1 Rabbit Polyclonal Antibody used for?

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.