Product details
Catalog number R1401-5
Price for R1401-5
Size / count 100 µL
Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V (D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system.In addition to its role in NHEJ, Ku is also required for telomere length maintenance and subtelomeric gene silencing. Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein.
The catalog number for Ku70 Rabbit Polyclonal Antibody is R1401-5.
Ku70 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.
Ku70 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.
Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V (D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian
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