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Product details

ATG12 Rabbit Polyclonal Antibody

Catalog number R1404-1

Price for R1404-1

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Size / count 100 µL

About this product

Autophagy-related protein 12 is a protein that in humans is encoded by the ATG12 gene. Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy. Autophagy requires the covalent attachment of the protein Atg12 to ATG5 through a ubiquitin-like conjugation system. The Atg12-Atg5 conjugate then promotes the conjugation of ATG8 to the lipid phosphatidylethanolamine. Atg12 was found to be involved in apoptosis. This protein promotes apoptosis through an interaction with anti-apoptotic members of the Bcl-2 family.

Specifications

Catalog number
R1404-1
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
APG12-like antibody APG12L antibody ATG12 antibody ATG12 autophagy related 12 homolog (S. cerevisiae) antibody ATG12 autophagy related 12 homolog antibody ATG12_HUMAN antibody Autophagy 12 antibody Autophagy-related protein 12 antibody FBR93 antibody HAPG12 antibody Ubiquitin-like protein ATG12 antibody
Abbreviation
APG12-like
Swiss Prot
O94817 Human
Cellular Locus
Cytoplasm
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human ATG12 aa 96-138.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Rat kidney, HCT116
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IF-Cell: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 15 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for ATG12 Rabbit Polyclonal Antibody?

The catalog number for ATG12 Rabbit Polyclonal Antibody is R1404-1.

What sizes are available for ATG12 Rabbit Polyclonal Antibody?

ATG12 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is ATG12 Rabbit Polyclonal Antibody in stock?

ATG12 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is ATG12 Rabbit Polyclonal Antibody used for?

Autophagy-related protein 12 is a protein that in humans is encoded by the ATG12 gene. Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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