KLHL15 Rabbit Polyclonal Antibody — image 1 of 3

Product details

KLHL15 Rabbit Polyclonal Antibody

Catalog number R1407-2

Price for R1407-2

Size / count 100 µL

About this product

Substrate-specific adapter for CUL3 E3 ubiquitin-protein ligase complex. Acts as an adapter for CUL3 to target the serine/threonine-protein phosphatase 2A (PP2A) subunit PPP2R5B for ubiquitination and subsequent proteasomal degradation, thus promoting exchange with other regulatory subunits. Acts as an adapter for CUL3 to target the DNA-end resection factor RBBP8/CtIP for ubiquitination and subsequent proteasomal degradation. Through the regulation of RBBP8/CtIP protein turnover, plays a key role in DNA damage response, favoring DNA double-strand repair through error-prone non-homologous end joining (NHEJ) over error-free, RBBP8-mediated homologous recombination (HR). This gene encodes a member of the kelch-like family of proteins that share a common domain structure consisting of an N-terminal broad-complex, tramtrack, bric-a-brac/poxvirus and zinc finger domain and C-terminal kelch repeat motifs. The encoded protein may be involved in protein ubiquitination and cytoskeletal organization.

Specifications

Catalog number: R1407-2
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Kelch like 15 (Drosophila) antibody Kelch like 15 antibody Kelch-like protein 15 antibody KIAA1677 antibody KLH15_HUMAN antibody KLHL15 antibody MGC126148 antibody MGC126149 antibody OTTHUMP00000023075 antibody
Abbreviation: KLHL15
Swiss Prot: Q96M94 Human
Cellular Locus: Cytoplasm
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human KLHL15 aa 555-604 / 604.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell
Positive Control: HEK-293 cell lysate, HeLa cell lysate, Jurkat cell lysate, Hela, PANC-1.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IF-Cell: 1:100-1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 70 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for KLHL15 Rabbit Polyclonal Antibody?

The catalog number for KLHL15 Rabbit Polyclonal Antibody is R1407-2.

What sizes are available for KLHL15 Rabbit Polyclonal Antibody?

KLHL15 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is KLHL15 Rabbit Polyclonal Antibody in stock?

KLHL15 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is KLHL15 Rabbit Polyclonal Antibody used for?

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.