ASH2L Rabbit Polyclonal Antibody

About this product

Transcriptional regulator . Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters . Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3 . May play a role in hematopoiesis (PubMed:12670868). In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B .

Specifications

Catalog number

R1408-1

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

ASH 2 antibody Ash2 (absent small or homeotic) like antibody Ash2 (absent, small, or homeotic) like (Drosophila) antibody ASH2 antibody ASH2 LIKE antibody ASH2 like protein antibody ASH2-like protein antibody Ash2l antibody ASH2L_HUMAN antibody ASH2L1 antibody ASH2L2 antibody Bre 2 antibody Bre2 antibody Discs 2-like antibody Drosophila absent, small, or homeotic antibody Drosophila ASH2-like antibody Set1/Ash2 histone methyltransferase complex subunit ASH2 antibody

Abbreviation

ASH2-like protein.ASH2L,Set1/Ash2 histone methyltransferase complex subunit ASH2

Swiss Prot

Q9UBL3 Human, Q91X20 Mouse

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within human ASH2L aa 575-628.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

Hela cell lysates, PC-12 cell lysates, mouse colon tissue, human breast carcinoma tissue, human colon tissue, Siha.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000;IHC-P: 1:100-1:500;FC: 1:50-1:100

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

59/57/60

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No