PTPRF/LAR Rabbit Polyclonal Antibody

About this product

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Specifications

Catalog number

R1510-12

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

FLJ43335 antibody FLJ45062 antibody FLJ45567 antibody LAR antibody LAR protein antibody LARFN5C antibody LARS antibody LCA homolog antibody Leukocyte antigen related (LAR) PTP receptor antibody Leukocyte antigen related antibody Leukocyte antigen related PTP receptor antibody Leukocyte antigen related tyrosine phosphatase antibody Leukocyte common antigen related antibody Protein Tyrosine Phosphatase Receptor Type F antibody Protein tyrosine phosphatase receptor type F polypeptide antibody Ptprf antibody PTPRF protein antibody PTPRF_HUMAN antibody Receptor linked protein tyrosine phosphatase LAR antibody Receptor type tyrosine protein phosphatase F antibody Receptor type tyrosine protein phosphatase F precursor antibody Receptor-type tyrosine-protein phosphatase F antibody

Abbreviation

LAR

Swiss Prot

P10586 Human

Cellular Locus

Membrane.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein with Human PTPRF / LAR aa 134-650 / 1,907.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

IF-Cell, IHC-P, FC

Positive Control

SiHa, human colon carcinoma tissue, human kidney tissue, A431.

Concentration

1 mg/mL

Dilution

IF-Cell: 1:200-1:500;IHC-P: 1:50-1:1,000;FC: 1:50-1:100

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 213 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

No