FPR2 Rabbit Polyclonal Antibody — image 1 of 3

Product details

FPR2 Rabbit Polyclonal Antibody

Catalog number R1510-13

Discontinued

Price for R1510-13

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

The N-formyl peptide receptor (FPR) family is comprised of three members, FPR, FPR2 (also designated lipoxin A4 receptor, FPRH1 and FPRL1) and FPR3 (also designated FPRL2), all of which are chemotactic G protein-coupled receptors that contain seven transmembrane domains. These receptors are found on the surface of phagocytic leukocytes, such as neutrophils and monocytes, and each family member contains specific residues, which are responsible for determining its ligand specificity. FPR2 is a promiscuous receptor that binds to several ligands, including lipoxin A4, N-formyl-methionyl-leucyl-phenylalanine (fMLP), serum amyloid A (SAA), prion peptide and the 42 amino acid form of ∫ amyloid. Upon activation, FPR2 induces migration and calcium mobilization in human monocytes and neutrophils and is involved in inflammatory and host defense responses. FPR2 may mediate inflammation in prion and Alzheimer’s diseases, which makes it a potential target for therapeutic agents.

Specifications

Catalog number: R1510-13
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9007-83-4
Product Name Alternative: ALXR antibody FMLP-R-I antibody FMLP-R-II antibody FMLP-related receptor I antibody FMLPX antibody Formyl peptide receptor 2 antibody Formyl peptide receptor related antibody Formyl peptide receptor-like 1 antibody FPR2 antibody FPR2_HUMAN antibody FPR2A antibody FPRH1 antibody FPRH2 antibody FPRL1 antibody HM63 antibody Lipoxin A4 receptor antibody LXA4 receptor antibody LXA4R antibody N-formyl peptide receptor 2 antibody RFP antibody
Abbreviation: FMLP-R-I,LXA4 receptor
Swiss Prot: O88536 Mouse
Cellular Locus: Cell membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within N-terminal mouse FPR2.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: IF-Cell, IHC-P, FC
Positive Control: HepG2, PC-3M, human lung cancer, mouse testis tissue, human spleen tissue, Jurkat.
Concentration: 1 mg/mL
Dilution: IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 39 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for FPR2 Rabbit Polyclonal Antibody?

The catalog number for FPR2 Rabbit Polyclonal Antibody is R1510-13.

Is FPR2 Rabbit Polyclonal Antibody in stock?

FPR2 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is FPR2 Rabbit Polyclonal Antibody used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.