Rem2 Rabbit Polyclonal Antibody

About this product

REM2 (RAS (RAD and GEM)-like GTP binding 2) is a 340 amino acid cell membrane protein that functions as a GTPase and belongs to the RGK family as well as the small GTPase superfamily. A suppressor of the p53 pathway, REM2 also mediates the fibroblastic growth factor 2 (FGF-2) signaling pathway and is involved in maintaining the proliferation of human embryonic stem cells. Expressed in kidney and brain, REM2 is encoded by a gene that maps to human chromosome 14q11.2. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Specifications

Catalog number

R1510-14

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

cb111 antibody chunp6884 antibody etID309896.20 antibody R2 antibody reductase M2 polypeptide variant 1 antibody reductase M2 polypeptide variant 2 antibody reductase M2 polypeptide variant 3a antibody reductase M2 polypeptide variant 3b antibody reductase M2 polypeptide variant 3c antibody reductase M2 polypeptide variant 3d antibody Ribonucleoside-diphosphate reductase subunit M2 antibody Ribonucleotide reductase M2 antibody Ribonucleotide reductase M2 polypeptide antibody Ribonucleotide reductase M2 subunit antibody ribonucleotide reductase protein r2 class I antibody Ribonucleotide reductase regulatory subunit M2 antibody Ribonucleotide reductase small chain antibody Ribonucleotide reductase small subunit antibody Ribonucleotide reductase, R2 subunit antibody RIR2_HUMAN antibody RR2 antibody RR2M antibody RRM2 antibody

Abbreviation

REM2

Swiss Prot

Q8IYK8 Human

Cellular Locus

Cell membrane.

Host

Rabbit

Species Reactivity

Human, Rat

Immunogen

Recombinant protein with Human Rem2 aa 121-292 / 340.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

IHC-P, FC

Positive Control

A549, HepG2, rat brain tissue, rat kidney tissue.

Concentration

1 mg/mL

Dilution

IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100;WB: 1:500

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 37 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

No