• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

TSC2/Tuberin Rabbit Polyclonal Antibody

Catalog number R1510-2

Price for R1510-2

Sign In for Pricing

Size / count 100 µL

About this product

Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each other forming a cystoplasmic complex. Hamartin interacts with the ezrin-radixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney.

Specifications

Catalog number
R1510-2
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
FLJ43106 antibody LAM antibody OTTHUMP00000158940 antibody OTTHUMP00000198394 antibody OTTHUMP00000198395 antibody PPP1R160 antibody Protein phosphatase 1, regulatory subunit 160 antibody tsc2 antibody TSC2_HUMAN antibody TSC4 antibody TSC4 gene, formerly antibody TSC4, formerly antibody Tuberin antibody Tuberous sclerosis 2 antibody Tuberous sclerosis 2 protein antibody Tuberous sclerosis 2 protein homolog antibody
Abbreviation
TSC2
Swiss Prot
P49815 Human
Cellular Locus
Cytoplasm, Membrane
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within Human TSC2 aa 1,758-1,807 / 1,807.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
IF-Cell, IHC-P, FC
Positive Control
SH-SY-5Y, PANC-1, human liver tissue, mouse brain tissue, human pancreas tissue, mouse pancreas tissue, mouse liver tissue.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:100-1:500 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for TSC2/Tuberin Rabbit Polyclonal Antibody?

The catalog number for TSC2/Tuberin Rabbit Polyclonal Antibody is R1510-2.

What sizes are available for TSC2/Tuberin Rabbit Polyclonal Antibody?

TSC2/Tuberin Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is TSC2/Tuberin Rabbit Polyclonal Antibody in stock?

TSC2/Tuberin Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is TSC2/Tuberin Rabbit Polyclonal Antibody used for?

Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

You Might Also Like
CD3e (CRIS-7), CF647 conjugate, 0.1mg/mL
CD3e (CRIS-7), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471050-100
Cytokeratin 8/18 (C-51), CF568 conjugate, 0.1mg/mL
Cytokeratin 8/18 (C-51), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680034-500
Major Vault Protein (MVP) (1032), CF488A conjugate, 0.1mg/mL
Major Vault Protein (MVP) (1032), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880225-500
Complement C4d (C4D204), CF568 conjugate, 0.1mg/mL
Complement C4d (C4D204), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680204-100
P27 / KIP1 (SX53G8), CF405S conjugate, 0.1mg/mL
P27 / KIP1 (SX53G8), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040669-500
CD71 (66IG10), CF647 conjugate, 0.1mg/mL
CD71 (66IG10), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470871-500
Cytokeratin, LMW (AE-1), CF647 conjugate, 0.1mg/mL
Cytokeratin, LMW (AE-1), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470253-500
CD47 (B6H12.2), CF740 conjugate, 0.1mg/mL
CD47 (B6H12.2), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740437-100