Metadherin (LYRIC) Rabbit Polyclonal Antibody — image 1 of 3

Product details

Metadherin (LYRIC) Rabbit Polyclonal Antibody

Catalog number R1511-10

Price for R1511-10

Size / count 100 µL

About this product

MTDH (metastasis adhesion protein), also known as astrocyte elevated gene-1 protein (AEG1) or lysine-rich CEACAM1 co-isolated protein (LYRIC), is a 582 amino acid single-pass membrane protein. Overexpressed in various cancers, MTDH activates the transcription factor NFκB and promotes anchorage-independent growth of immortalized astrocytes and melanocytes, which are key components of tumor growth. MTDH is also thought to enhance the seeding of tumor cells to the target organ endothelium. Localized mainly to the endoplasmic reticulum membrane, MTDH also translocates from the cytoplasm to the nucleus when induced by TNFα. MTDH also localizes to tight junctions (TJ) during the maturation of TJ complexes in epithelial cells. MTDH is found at highest levels in heart, skeletal muscle, tongue and small intestine.

Specifications

Catalog number: R1511-10
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 3D3 antibody 3D3/LYRIC antibody AEG 1 antibody AEG-1 antibody AEG1 antibody Astrocyte elevated gene 1 antibody Astrocyte elevated gene-1 protein antibody LYRIC antibody LYRIC/3D3 antibody LYRIC_HUMAN antibody Lysine rich CEACAM1 associated protein antibody Lysine rich CEACAM1 co isolated protein antibody Lysine-rich CEACAM1 co-isolated protein antibody Metadherin antibody Metastasis adhesion protein antibody MTDH antibody Protein LYRIC antibody
Abbreviation: AEG-1,MTDH
Swiss Prot: Q86UE4 Human
Cellular Locus: Endoplasmic reticulum membrane. Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within human Metadherin aa 18-253.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: Human skeletal muscle tissue lysate, MCF-7, Hela, N2A, SH-SY5Y, human breast tissue, mouse brain tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:100-1:500;FC: 1:50-1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 64 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Metadherin (LYRIC) Rabbit Polyclonal Antibody?

The catalog number for Metadherin (LYRIC) Rabbit Polyclonal Antibody is R1511-10.

What sizes are available for Metadherin (LYRIC) Rabbit Polyclonal Antibody?

Metadherin (LYRIC) Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Metadherin (LYRIC) Rabbit Polyclonal Antibody in stock?

Metadherin (LYRIC) Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Metadherin (LYRIC) Rabbit Polyclonal Antibody used for?

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.