Figla Rabbit Polyclonal Antibody

Catalog number R1511-28

Price for R1511-28

Size / count 100 µL

About this product

Ovarian folliculogenesis is an intricate process involving interactions between germ and somatic cells in mammalians. FIGLA (folliculogenesis specific basic helix-loop-helix), also known as POF6, BHLHC8 or FIGALPHA, is a 219 amino acid nuclear protein expressed in fetal ovary and germ cells. FIGLA contains one basic helix-loop-helix (bHLH) domain and heterodimerizes with E12, a transcription factor that influences gene expression during B cell maturation. Acting as a germline specific transcription factor and a key player of ovarian folliculogenesis, FIGLA regulates the expression of multiple oocyte-specific genes that are required for fertilization and early embryonic survival. Mutations in the gene encoding FIGLA may be the cause of Premature Ovarian Failure (POF), a genetically heterogenous disorder that leads to hypergonadotropic ovarian failure and infertility. POF is characterized by amenorrhea, hypoestrogenism and elevated serum gonadotropin concentrations. FIGLA inhibits the expression of male germ cell specific genes during oogenesis.

Specifications

Catalog number: R1511-28
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: bHLHc8 antibody Class C basic helix-loop-helix protein 8 antibody Factor in the germline alpha antibody FIGalpha antibody FIGLA antibody FIGLA_HUMAN antibody Folliculogenesis specific basic helix loop helix antibody Folliculogenesis-specific basic helix-loop-helix protein antibody POF6 antibody Transcription factor FIGa antibody
Abbreviation: FIGalpha
Swiss Prot: O55208 Mouse
Cellular Locus: Cytoplasm
Host: Rabbit
Species Reactivity: Mouse
Immunogen: Synthetic peptide within Human Figla aa 21-70 / 219.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: IF-Cell
Positive Control: Mouse three-cell embryos
Concentration: 1 mg/mL
Dilution: IF-Cell: 1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Figla Rabbit Polyclonal Antibody?

The catalog number for Figla Rabbit Polyclonal Antibody is R1511-28.

What sizes are available for Figla Rabbit Polyclonal Antibody?

Figla Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Figla Rabbit Polyclonal Antibody in stock?

Figla Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Figla Rabbit Polyclonal Antibody used for?

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.